Development of an activity index for adult eosinophilic esophagitis: international experts propose dysphagia, withish exudates on endoscopy and peripheral eosinophilia as items with closest association to EoE activity

Détails

ID Serval
serval:BIB_F72C8AA2C6F3
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Poster: résume de manière illustrée et sur une page unique les résultats d'un projet de recherche. Les résumés de poster doivent être entrés sous "Abstract" et non "Poster".
Collection
Publications
Institution
Titre
Development of an activity index for adult eosinophilic esophagitis: international experts propose dysphagia, withish exudates on endoscopy and peripheral eosinophilia as items with closest association to EoE activity
Titre de la conférence
Annual Meeting of the Swiss Society of Gastroenterology, Swiss Society for Visceral Surgery, Swiss Association for the Study of the Liver, Swiss Association of Clinical Nutrition
Auteur⸱e⸱s
Schoepfer A.M., Maurer E., Kuehni C., Zwahlen M., Jost C., Ortner M., Macpherson A.J., Straumann A.
Adresse
Interlaken, Switzerland, September 23-24, 2010
ISBN
1424-7860
Statut éditorial
Publié
Date de publication
2010
Volume
140
Série
Swiss Medical Weekly
Pages
13S
Langue
anglais
Résumé
Background and Aims: Eosinophilic Esophagitis (EoE) is
reported with increasing frequency over the last two decades.
However, it is still unknown whether this reflects a true increase
in incidence or just an increased awareness by
gastroenterologists. Therefore, we evaluated the incidence and
cumulative prevalence of EoE in Olten county over the last 20
years.
Methods: Olten county is an area of approximately
91,000 inhabitants without pronounced demographic changes in
the last two decades. EoE evaluation is based upon two
gastroenterology centers and one pathology center. No public
programs for increased EoE awareness were implemented in
this region. All EoE patients diagnosed from 1989 to 2009 were
entered prospectively into the Olten county database.
Results: Fourty-six patients (76% males, mean age 41±16 yrs)
were diagnosed with EoE from 1989 to 2009. Ninety-four
percent presented with dysphagia. In 70% of the patients
concomitant allergies were found. The number of upper
endoscopies per year was stable during the entire observation
period. An average annual incidence rate of 2/100,000 was
found (range 0-8) with a marked increase in the period from
2001 to 2009. A current cumulative EoE prevalence of
43/100,000 inhabitants was calculated. The mean diagnostic
delay (time from first symptoms to diagnosis) was 4.3 years
from 1989 to 1998 and 4.8 years from 1999 to 2009.
Conclusions: Over the last 20 years, a significant increase in
EoE incidence was found in a stable indicator region of
Switzerland. The constant rate of upper endoscopies, the
constant diagnostic delay, as well as the lack of EoE awareness
programs in Olten county indicate a true increase in EoE
incidence.
Web of science
Création de la notice
02/02/2011 11:25
Dernière modification de la notice
20/08/2019 17:23
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