S-nitrosylation of proteins

Détails

ID Serval
serval:BIB_F6E47C3C2B1B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
S-nitrosylation of proteins
Périodique
Cellular and Molecular Life Sciences
Auteur(s)
Broillet  M. C.
ISSN
1420-682X (Print)
Statut éditorial
Publié
Date de publication
07/1999
Volume
55
Numéro
8-9
Pages
1036-42
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Jul
Résumé
The transfer of a nitric oxide group to cysteine sulfhydryls on proteins, known as S-nitrosylation, is increasingly becoming recognized as a ubiquitous regulatory reaction comparable to phosphorylation. It represents a form of redox modulation in diverse tissues, including the brain. An increasing number of proteins have been found to undergo S-nitrosylation in vivo. These proteins are called S-nitrosothiols, and may play an important role in many processes ranging from signal transduction, DNA repair, host defense, and blood pressure control to ion channel regulation and neurotransmission. This review focuses on the importance of the S-nitrosylation reaction and describes some recently identified S-nitrosothiols in various fields of research.
Mots-clé
Animals Apoptosis/physiology Arginine/metabolism Cyclic GMP/metabolism Cysteine/metabolism HIV Protease/metabolism Hemoglobins/metabolism Humans Immune System/physiology Ion Transport/physiology Macrophages/physiology Nitric Oxide/*metabolism Nitroso Compounds/*metabolism Oxidation-Reduction Platelet Aggregation/physiology *Protein Processing, Post-Translational Signal Transduction/physiology
Pubmed
Web of science
Création de la notice
24/01/2008 12:01
Dernière modification de la notice
20/08/2019 17:23
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