Cerebral blood flow and mental processes in schizophrenia.

Détails

ID Serval
serval:BIB_F39661F4AAEB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Cerebral blood flow and mental processes in schizophrenia.
Périodique
Journal of the Royal Society of Medicine
Auteur⸱e⸱s
Liddle P.F., Friston K.J., Frith C.D., Frackowiak R.S.
ISSN
0141-0768 (Print)
ISSN-L
0141-0768
Statut éditorial
Publié
Date de publication
1992
Volume
85
Numéro
4
Pages
224-227
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
The patterns of cerebral blood flow associated with three syndromes of schizophrenic symptoms are compared with the loci of cerebral activation in normal subjects during the performance of mental processes implicated in the three syndromes. The psychomotor poverty syndrome, which has been shown to involve a diminished ability to generate words, is associated with decreased perfusion of the dorsolateral prefrontal cortex at a locus which is activated in normal subjects during the internal generation of words. The disorganization syndrome, which has been shown to involve impaired suppression of inappropriate responses (eg in the Stroop test), is associated with increased perfusion of the right anterior cingulate gyrus at a location activated in normal subjects performing the Stroop test. The reality distortion syndrome, which evidence suggests arises from disordered internal monitoring of activity, is associated with increased perfusion in the medial temporal lobe at a locus activated in normal subjects during the internal monitoring of eye movements.
Mots-clé
Adult, Brain/radionuclide imaging, Cerebrovascular Circulation/physiology, Humans, Mental Processes/physiology, Schizophrenia/physiopathology, Schizophrenia/radionuclide imaging, Tomography, Emission-Computed
Pubmed
Web of science
Création de la notice
25/09/2011 17:22
Dernière modification de la notice
20/08/2019 17:20
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