Ultrasound navigation through the heart for off-pump aortic valved stent implantation: new tools for new goals

Détails

ID Serval
serval:BIB_F343CC35110C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Ultrasound navigation through the heart for off-pump aortic valved stent implantation: new tools for new goals
Périodique
Journal of Endovascular Therapy
Auteur(s)
Huber  C. H., Nasratulla  M., Augstburger  M., von Segesser  L. K.
ISSN
1526-6028
Statut éditorial
Publié
Date de publication
08/2004
Peer-reviewed
Oui
Volume
11
Numéro
4
Pages
503-10
Notes
Journal Article
Validation Studies --- Old month value: Aug
Résumé
PURPOSE: To validate the use of simultaneous intracardiac and intravascular ultrasound (IVUS) guidance for periprocedural dimension assessment, Residual-Coronary/Sinus-Stent Index (RCSSI) estimation, target site identification, deployment monitoring, and quality control of off-pump aortic Valved Stent implantation. METHODS: Five pigs (56+/-5 kg) underwent off-pump orthotopic aortic valve implantation using a custom-made self-expanding Valved Stent. Intracardiac ultrasound (AcuNav) was introduced via the right femoral vein. After left-sided thoracotomy, pursestring sutures were placed on the left ventricular apex. Following heparinization, a guidewire was inserted through the apex and advanced over the aortic valve under fluoroscopy. A wire-guided IVUS catheter transducer (6-F, 12.5-MHz) was inserted and the aortic target site identified. IVUS probe location was tracked with AcuNav, and measures of the aortic root were taken by both. After removal of the IVUS, the Valved Stent delivery system was introduced over the guidewire under fluoroscopy and AcuNav monitoring; the Valved Stent was deployed over the native valves. In vivo assessment included leaflet motion, planimetric valve orifice and RCSSI (stent to aortic wall distance/coronary diameter) calculations, coronary blood flow characteristics, transvalvular gradient, regurgitation, and paravalvular leaking in combination with continuous cardiac output measures. Macroscopic analysis was performed at necropsy. RESULTS: IVUS dimensions of the aortic root were equal to AcuNav and necropsy dimensions. Both tools showed good valvular function, with full valvular opening and closing in 3 of 5 valves. At necropsy, the 3 aortic Valved Stents were safely anchored. One Valved Stent was placed supra-annularly; 2 dislodged into the left ventricle because of size mismatch. One Valved Stent showed a moderate to severe paravalvular leak. CONCLUSIONS: Simultaneous intracardiac and intravascular ultrasound-guided off-pump orthotopic aortic Valved Stent implantation via left sided thoracotomy is feasible in an animal model. IVUS and intracardiac ultrasound allow adequate aortic dimension assessment and Valved Stent delivery monitoring, as well as postimplantation coronary flow evaluation.
Mots-clé
Animals Aortic Valve/physiopathology/*surgery/*ultrasonography Cardiac Output/physiology Coronary Circulation/physiology Feasibility Studies Heart Valve Prosthesis Implantation/*methods *Stents Swine *Ultrasonography, Interventional
Pubmed
Web of science
Création de la notice
29/01/2008 14:45
Dernière modification de la notice
20/08/2019 16:20
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