Detecting, quantifying and adjusting for publication bias in meta-analyses: protocol of a systematic review on methods.

Détails

Ressource 1Télécharger: BIB_F243416EA32C.P001.pdf (164.11 [Ko])
Etat: Public
Version: de l'auteur⸱e
ID Serval
serval:BIB_F243416EA32C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Detecting, quantifying and adjusting for publication bias in meta-analyses: protocol of a systematic review on methods.
Périodique
Systematic Reviews
Auteur⸱e⸱s
Mueller K.F., Meerpohl J.J., Briel M., Antes G., von Elm E., Lang B., Gloy V., Motschall E., Schwarzer G., Bassler D.
ISSN
2046-4053 (Electronic)
ISSN-L
2046-4053
Statut éditorial
Publié
Date de publication
2013
Volume
2
Pages
60
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: epublish
Résumé
BACKGROUND: Health professionals and policymakers aspire to make healthcare decisions based on the entire relevant research evidence. This, however, can rarely be achieved because a considerable amount of research findings are not published, especially in case of 'negative' results - a phenomenon widely recognized as publication bias. Different methods of detecting, quantifying and adjusting for publication bias in meta-analyses have been described in the literature, such as graphical approaches and formal statistical tests to detect publication bias, and statistical approaches to modify effect sizes to adjust a pooled estimate when the presence of publication bias is suspected. An up-to-date systematic review of the existing methods is lacking.
METHODS/DESIGN: The objectives of this systematic review are as follows:âeuro¢ To systematically review methodological articles which focus on non-publication of studies and to describe methods of detecting and/or quantifying and/or adjusting for publication bias in meta-analyses.âeuro¢ To appraise strengths and weaknesses of methods, the resources they require, and the conditions under which the method could be used, based on findings of included studies.We will systematically search Web of Science, Medline, and the Cochrane Library for methodological articles that describe at least one method of detecting and/or quantifying and/or adjusting for publication bias in meta-analyses. A dedicated data extraction form is developed and pilot-tested. Working in teams of two, we will independently extract relevant information from each eligible article. As this will be a qualitative systematic review, data reporting will involve a descriptive summary.
DISCUSSION: Results are expected to be publicly available in mid 2013. This systematic review together with the results of other systematic reviews of the OPEN project (To Overcome Failure to Publish Negative Findings) will serve as a basis for the development of future policies and guidelines regarding the assessment and handling of publication bias in meta-analyses.
Pubmed
Open Access
Oui
Création de la notice
22/09/2013 23:28
Dernière modification de la notice
20/08/2019 17:19
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