Approach to oligometastatic disease in head and neck cancer, on behalf of the GORTEC.
Détails
ID Serval
serval:BIB_F163EA163C89
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Approach to oligometastatic disease in head and neck cancer, on behalf of the GORTEC.
Périodique
Future oncology
ISSN
1744-8301 (Electronic)
ISSN-L
1479-6694
Statut éditorial
Publié
Date de publication
04/2018
Peer-reviewed
Oui
Volume
14
Numéro
9
Pages
877-889
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Median survival for recurrent/metastatic head and neck squamous cell cancer (HNSCC) patients is about 10 months after first-line best systemic treatment. We aimed to assess current approaches of oligometastatic HNSCC patients by the analysis of current concept and published data (1995-2017) in this population. Five-year survival rates are over 20% in selected patients who undergo metastasis-directed therapy by either surgery or stereotactic irradiation. Human papillomavirus(+) HNSCC patients have more disseminated metastases but respond more favorably and also benefit from ablative treatments. Treatments of oligometastases are expanding rapidly. Unmet needs include revised imaging follow-up strategies to detect metastases earlier, identification of predictive noninvasive biomarkers for treatment guidance, assessment and corrections of biases in current studies and randomized clinical trials.
Mots-clé
Biomarkers, Tumor/genetics, Carcinoma, Squamous Cell/drug therapy, Carcinoma, Squamous Cell/genetics, Carcinoma, Squamous Cell/radiotherapy, Carcinoma, Squamous Cell/surgery, Head and Neck Neoplasms/drug therapy, Head and Neck Neoplasms/genetics, Head and Neck Neoplasms/radiotherapy, Head and Neck Neoplasms/surgery, Humans, Neoplasm Metastasis, Neoplasm Recurrence, Local/drug therapy, Neoplasm Recurrence, Local/genetics, Neoplasm Recurrence, Local/radiotherapy, Neoplasm Recurrence, Local/surgery, Radiosurgery, Randomized Controlled Trials as Topic, ablative treatment, head and neck cancer, immunotherapy, metastasectomy, metastases, metastasis-directed treatment, oligometastases, stereotactic irradiation
Pubmed
Web of science
Création de la notice
29/03/2018 17:50
Dernière modification de la notice
20/08/2019 16:18