Tectonic epikeratoplasty with ethanol-stored donor corneas.

Détails

ID Serval
serval:BIB_F01CF2865BA1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Tectonic epikeratoplasty with ethanol-stored donor corneas.
Périodique
Cell and tissue banking
Auteur(s)
Lazaridis A., Brouzas D., Sekundo W., Georgalas I., Kymionis G., Chatzistefanou K., Koutsandrea C., Droutsas K.
ISSN
1573-6814 (Electronic)
ISSN-L
1389-9333
Statut éditorial
Publié
Date de publication
12/2018
Peer-reviewed
Oui
Volume
19
Numéro
4
Pages
637-644
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
To evaluate the efficacy and outcomes of tectonic epikeratoplasty with use of ethanol-preserved corneal grafts for the management of perforated corneal melts. The present retrospective case series includes 10 eyes which underwent tectonic epikeratoplasty for perforated corneal melts. The stromal remainders of Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK) graft preparation were stored in 95% ethanol and used as emergency tectonic grafts for restoring globe integrity after sterile and infectious perforated corneal melts. In 6 cases with subtotal corneal melt, DMEK remainders (endothelium-denuded corneoscleral buttons) were used for 'limbus to limbus' tectonic epikeratoplasty and in 4 cases DSAEK remainders (anterior stroma) were used to seal focal perforated melts. Graft storage time was 5.1 ± 4.9 (ranging from 0.5 to 17) months. The surgeries were successful in all cases with restitution of the globe integrity. During the postoperative course 4 cases developed a graft melt (corneoscleral button for limbus to limbus tectonic epikeratoplasty, n = 3; lamellar patch, n = 1) within 2-6 months after the initial procedure. Three patients underwent successful repeat tectonic epikeratoplasty. In the fourth case of graft melt the globe was enucleated due to underlying expulsive haemorrhage and severe pain. The short-term results of the present case series suggest that the use of ethanol-stored stromal remainder of donor corneas after endothelial keratoplasty is an efficient temporary measure for tectonic restoration of perforated corneas.
Mots-clé
Adult, Aged, Cornea/surgery, Epikeratophakia, Ethanol/chemistry, Female, Graft Survival, Humans, Male, Middle Aged, Tissue Donors, Corneal melt, Ethanol, Perforation, Tectonic epikeratoplasty
Pubmed
Web of science
Création de la notice
30/01/2019 14:57
Dernière modification de la notice
20/08/2019 17:17
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