Antioxidant status of neonates exposed in utero to tobacco smoke.

Détails

ID Serval
serval:BIB_ED05A66BB5BB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Antioxidant status of neonates exposed in utero to tobacco smoke.
Périodique
Biology of the Neonate
Auteur(s)
Fayol L., Gulian J.M., Dalmasso C., Calaf R., Simeoni U., Millet V.
ISSN
0006-3126 (Print)
ISSN-L
0006-3126
Statut éditorial
Publié
Date de publication
2005
Peer-reviewed
Oui
Volume
87
Numéro
2
Pages
121-126
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish
Résumé
To investigate the influence of maternal smoke exposure on neonatal and maternal antioxidant status, 39 mothers who were active smokers, 14 mothers exposed to environmental tobacco smoke (ETS), 17 controls, and their newborns were included in a prospective, controlled study. Plasma total antioxidant capacity, measured as total radical-trapping antioxidant parameter (TRAP) and ferric reducing antioxidant power (FRAP), and concentrations of specific antioxidants were measured in cord and in maternal blood. A similar, significant increase in ceruloplasmin concentration was observed in neonates born to actively smoking mothers and in those born to ETS exposed mothers. Uric acid and TRAP concentrations were significantly increased in ETS-exposed newborns and their mothers, compared to newborns and mothers from the active smoking and no-exposure groups with a trend towards increased uric acid, TRAP and FRAP concentrations being observed in the active smokers group. Neonatal and maternal antioxidant concentrations correlated significantly, except for ceruloplasmin. Cord blood vitamin A, E and C concentrations were unaffected by smoke exposure. These results show that maternal active smoking as well as ETS exposure significantly affect neonatal and maternal antioxidant status.
Mots-clé
Adult, Antioxidants/analysis, Ascorbic Acid/blood, Ceruloplasmin/analysis, Female, Ferric Compounds/chemistry, Fetal Blood/chemistry, Free Radicals/chemistry, Humans, Infant, Newborn, Maternal-Fetal Exchange, Pregnancy, Prospective Studies, Smoking/adverse effects, Tobacco Smoke Pollution/adverse effects, Uric Acid/blood, Vitamin A/blood, Vitamin E/blood
Pubmed
Web of science
Création de la notice
22/02/2015 9:16
Dernière modification de la notice
20/08/2019 16:14
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