Social phobia is associated with suicide attempt history in bipolar inpatients

Détails

ID Serval
serval:BIB_ECF66E2B147A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Social phobia is associated with suicide attempt history in bipolar inpatients
Périodique
BIPOLAR DISORD
Auteur⸱e⸱s
Perroud Nader, Baud Patrick, Preisig Martin, Etain Bruno, Bellivier Frank, Favre Sophie, Reber Nadja, Ferrero François, Leboyer Marion, Malafosse Alain
ISSN
1398-5647
Statut éditorial
Publié
Date de publication
2007
Peer-reviewed
Oui
Volume
9
Numéro
7
Pages
713-721
Langue
anglais
Notes
SAPHIRID:63942
Résumé
Objectives: In an attempt to reduce the phenotypical heterogeneity in an ongoing genetic study of suicidal behavior, we investigated the impact of comorbid anxiety disorders on suicidal behavior in bipolar disorder (BD) patients.
Methods: Anxiety disorders were compared in 406 BD I and BD II patients with or without lifetime history of suicide attempt.
Results: Among anxiety disorders, only social phobia (SP) was significantly associated with history of suicide attempt in BD [p < 0.001, odds ratio 4.26 (2.284-7.946)]. Moreover, onset of SP was found to precede onset of BD.
Conclusions: This result suggests that SP is an important risk factor for suicidal behavior in BD. Further studies are required to determine whether comorbid SP may help to identify a more homogeneous BD sub-group, especially when studies of suicidal behavior are conducted. A second question is whether SP identifies a sub-group of subjects with BD who have a more severe illness course and whether treatment of SP with selective serotonin reuptake inhibitor (SSRI) antidepressants is associated with improvement or worsening of the course of BD.
Web of science
Création de la notice
13/03/2008 8:39
Dernière modification de la notice
20/08/2019 16:14
Données d'usage