Process variations between Swiss units treating neonates with hypoxic-ischemic encephalopathy and their effect on short-term outcome.
Détails
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Etat: Public
Version: Final published version
Licence: Non spécifiée
ID Serval
serval:BIB_EC7D73520751
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Process variations between Swiss units treating neonates with hypoxic-ischemic encephalopathy and their effect on short-term outcome.
Périodique
Journal of perinatology
Collaborateur⸱rice⸱s
Swiss National Asphyxia and Cooling Register Group
Contributeur⸱rice⸱s
Bassler D., Natalucci G., Böttger S., Frey B., Bernet V., Grass B., Rogdo B., Hoigné I., Stocker M., Berger T.M., Fontana M., Hegi L., Meyer P., Konetzny G., Schulzke S.M., Wellmann S., Hug M., Humpl T., Wagner B., Daetwyler K., Riedel T., Scharrer B., Binz N., Truttmann A., Schneider J.
ISSN
1476-5543 (Electronic)
ISSN-L
0743-8346
Statut éditorial
Publié
Date de publication
12/2021
Peer-reviewed
Oui
Volume
41
Numéro
12
Pages
2804-2812
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
To compare therapeutic hypothermia (TH) treatment of term and near-term neonates with hypoxic-ischemic encephalopathy (HIE) between neonatal units.
Population-based, retrospective analysis of TH initiation and maintenance, and of diagnostic imaging. The comparison between units was based on crude data analysis, indirect standardization, and adjusted logistic regression.
TH was provided to 570 neonates with HIE between 2011 and 2018 in 10 Swiss units. We excluded 121 off-protocol cooled neonates to avoid selection bias. Of the remaining 449 neonates, the outcome was favorable to international benchmarks, but there were large unit-to-unit variations in baseline perinatal data and TH management. A total of 5% neonates did not reach target temperature within 7 h (3-10% between units), and 29% experienced over- or undercooling (0-38%).
Although the neonates had favorable short-term outcomes, areas for improvement remain for Swiss units in both process and outcome measures.
Population-based, retrospective analysis of TH initiation and maintenance, and of diagnostic imaging. The comparison between units was based on crude data analysis, indirect standardization, and adjusted logistic regression.
TH was provided to 570 neonates with HIE between 2011 and 2018 in 10 Swiss units. We excluded 121 off-protocol cooled neonates to avoid selection bias. Of the remaining 449 neonates, the outcome was favorable to international benchmarks, but there were large unit-to-unit variations in baseline perinatal data and TH management. A total of 5% neonates did not reach target temperature within 7 h (3-10% between units), and 29% experienced over- or undercooling (0-38%).
Although the neonates had favorable short-term outcomes, areas for improvement remain for Swiss units in both process and outcome measures.
Mots-clé
Female, Humans, Hypothermia, Induced, Hypoxia-Ischemia, Brain/therapy, Infant, Newborn, Pregnancy, Retrospective Studies, Switzerland, Temperature
Pubmed
Web of science
Open Access
Oui
Création de la notice
27/02/2024 11:07
Dernière modification de la notice
09/08/2024 14:53
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