ADH1 expression inversely correlates with CDR1 and CDR2 in Candida albicans from chronic oral candidosis in APECED (APS-I) patients.
Détails
ID Serval
serval:BIB_E6EAC763E927
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
ADH1 expression inversely correlates with CDR1 and CDR2 in Candida albicans from chronic oral candidosis in APECED (APS-I) patients.
Périodique
Fems Yeast Research
ISSN
1567-1364 (Electronic)
ISSN-L
1567-1356
Statut éditorial
Publié
Date de publication
2011
Volume
11
Numéro
6
Pages
494-8
Langue
anglais
Résumé
Expression of the alcohol dehydrogenase gene ADH1, which converts ethanol into carcinogenic acetaldehyde, significantly inversely correlated with the expression of CDR1 and CDR2, genes linked to azole resistance in Candida albicans isolated from chronic oral candidosis in autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy (APECED, APS-I) patients. This is a novel link between candidal two-carbon metabolism genes and azole resistance.
Pubmed
Web of science
Open Access
Oui
Création de la notice
01/09/2011 9:54
Dernière modification de la notice
20/08/2019 17:10
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