Mood and anxiety profiles differentially associate with physical conditions in US adolescents.

Détails

ID Serval
serval:BIB_E50E2F25D516
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Mood and anxiety profiles differentially associate with physical conditions in US adolescents.
Périodique
Journal of affective disorders
Auteur⸱e⸱s
Stapp E.K., Paksarian D., He J.P., Glaus J., Conway K.P., Merikangas K.R.
ISSN
1573-2517 (Electronic)
ISSN-L
0165-0327
Statut éditorial
Publié
Date de publication
15/02/2022
Peer-reviewed
Oui
Volume
299
Pages
22-30
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural
Publication Status: ppublish
Résumé
Mood and anxiety are widely associated with physical conditions, but research and treatment are complicated by their overlap, clinical heterogeneity, and manifestation on a spectrum rather than as discrete disorders. In contrast to previous work relying on threshold-level disorders, we examined the association between empirically-derived profiles of mood and anxiety syndromes with physical conditions in a nationally-representative sample of US adolescents.
Participants were 2,911 adolescents (aged 13-18) from the National Comorbidity Survey-Adolescent Supplement who provided information on physical conditions and reported at least one lifetime mood-anxiety 'syndrome' based on direct interviews with the Composite International Diagnostic Interview Version 3.0. Mood-anxiety syndromes reflected 3-level ratings from subthreshold to severe distress/impairment, and subtyped mood episodes. Stepwise latent profile analysis identified mood-anxiety profiles and tested associations with physical conditions.
Three mood-anxiety profiles were identified: "Mood-GAD" (25.6%)-non-atypical depression, mania, generalized anxiety; "Atypical-Panic" (11.3%)-atypical depression, panic; and "Reference" (63.1%)-lower mood and anxiety except specific phobia. Headaches were more prevalent in Mood-GAD and Atypical-Panic than Reference (47.9%, 50.1%, and 37.7%, respectively; p=0.011). Heart problems were more common in Mood-GAD than Atypical-Panic (7.4% v 2.2%, p=0.004) and Reference, with back/neck pain more prevalent in Mood-GAD than Reference (22.5% v 15.3%, p=0.016).
Broad categories of physical conditions without information on specific diagnoses; replication regarding specificity is recommended.
Heart problems and pain-related conditions were differentially associated with specific mood-anxiety profiles. Subtyping depression and anxiety-inclusive of subthreshold syndromes-and their patterns of clustering may facilitate etiologic and intervention work in multimorbidity.
Mots-clé
Adolescent, Anxiety/epidemiology, Anxiety Disorders/diagnosis, Anxiety Disorders/epidemiology, Comorbidity, Humans, Panic, Phobic Disorders, Prevalence, Anxiety disorders, Chronic pain, Headache, Heart diseases, Mood disorders
Pubmed
Web of science
Création de la notice
03/12/2021 11:36
Dernière modification de la notice
29/03/2022 6:36
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