Construction d'une matrice emplois-expositions pour le suivi épidémiologique des travailleurs de l'industrie nucléaire en France. Résultats d'une étude pilote [Development of a job exposure matrix for the epidemiological follow-up of workers in the French nuclear industry]

Détails

ID Serval
serval:BIB_E361D39E2B2C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Construction d'une matrice emplois-expositions pour le suivi épidémiologique des travailleurs de l'industrie nucléaire en France. Résultats d'une étude pilote [Development of a job exposure matrix for the epidemiological follow-up of workers in the French nuclear industry]
Périodique
Revue d'épidemiologie et de santé publique
Auteur⸱e⸱s
Guseva Canu Irina, Molina Gilbert, Goldberg Marcel, Collomb Philippe, David Jean-Claude, Perez Patrice, Paquet François, Tirmarche Margot
ISSN
0398-7620 (Print)
ISSN-L
0398-7620
Statut éditorial
Publié
Date de publication
02/2008
Peer-reviewed
Oui
Volume
56
Numéro
1
Pages
21-29
Langue
français
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Résumé
A pilot study was carried out in the AREVA NC Pierrelatte nuclear facility in order to investigate a possible carcinogenic effect of internal radiation exposure among nuclear workers in France. The objective of this study was to develop a method for retrospective reconstruction of the occupational exposure to internal radiation from uranium and associated chemical exposures.
A plant- and period-specific job exposure matrix (JEM) was designed. Job groups and exposure agents groups including uranium compounds and other chemical agents known as being carcinogenic, mutagenic or toxic were defined by an expert committee. Exposure was evaluated by active and retired workers included in the evaluator committee. A quantitative assignment of quantity and frequency of handling (both coded from 0 to 3) was performed for each agent groups using a method derived from the Delphi technique.
In all, 23 experts and 353 evaluators participated to the JEM elaboration. A final JEM involved 232 "job-periods" presenting throughout the plant period 1960-2006 and 22 exposure agents groups in use at the plant. Six of them involved uranium compounds classified by their blood-transferability and toxicity characteristics. A first validation of the JEM by experts in radiological protection and industrial hygiene showed an acceptable internal consistency.
In the context of missing past exposure measurement data, the plant- and period-specific job exposure matrices may be considered as a valid alternative for exposure estimation. This method may be applied to other nuclear plants and offers allowance to investigate a possible carcinogenic effect of internal radiation exposure among nuclear workers.

Mots-clé
France, Humans, Neoplasms/prevention & control, Nuclear Reactors, Occupational Exposure/analysis, Pilot Projects, Radiation Injuries/prevention & control, Risk Assessment
Pubmed
Web of science
Création de la notice
12/09/2017 15:31
Dernière modification de la notice
20/08/2019 16:07
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