Mitomycin C for control of recurrent bronchial stenosis: a case report.

Détails

ID Serval
serval:BIB_DF4DEAC5D563
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Mitomycin C for control of recurrent bronchial stenosis: a case report.
Périodique
Chest
Auteur⸱e⸱s
Erard A.C., Monnier P., Spiliopoulos A., Nicod L.
ISSN
0012-3692[print], 0012-3692[linking]
Statut éditorial
Publié
Date de publication
2001
Volume
120
Numéro
6
Pages
2103-2105
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Résumé
A 27-year-old patient with cystic fibrosis underwent a bilateral lung transplantation despite the presence of multiresistant Burkholderia cepacia. Postoperatively, the patient presented with bilateral bronchial necrosis. During the 14th week, his FEV(1) dropped to 2.5 L from a baseline level of 3.4 L. A subtotal occlusion of the right mainstem bronchus below the suture was noted. Using argon electrocoagulation, the right upper lobe bronchus, the intermediate bronchus, and the right middle lobe bronchus were reopened. During the period between weeks 20 and 42 post-transplantation, a recurrent stenosis required eight endoscopic interventions combining dilatation and stenting. During the 42nd week, dilatation followed by mitomycin C application stabilized the right lung function. This case report is the first to describe the effectiveness of the local application of mitomycin C to stop recurring extensive bronchial stenosis following bronchial necrosis secondary to lung transplantation.
Mots-clé
Administration, Topical, Adult, Airway Obstruction/drug therapy, Bronchi/pathology, Bronchial Diseases/drug therapy, Cystic Fibrosis/surgery, Dilatation, Humans, Lung Transplantation, Male, Mitomycin/administration & dosage, Mitomycin/adverse effects, Necrosis, Recurrence
Pubmed
Web of science
Création de la notice
19/02/2010 19:01
Dernière modification de la notice
20/08/2019 16:03
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