Priming cardiac function with voluntary respiratory maneuvers and effect on early exercise oxygen uptake.

Détails

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Etat: Public
Version: Author's accepted manuscript
Licence: Non spécifiée
ID Serval
serval:BIB_DF31B460BE2E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Priming cardiac function with voluntary respiratory maneuvers and effect on early exercise oxygen uptake.
Périodique
Journal of applied physiology
Auteur⸱e⸱s
Stucky F., Churchill T.W., Churchill J.L., Petek B.J., Guseh J.S., Wasfy M.M., Kayser B., Baggish A.L.
ISSN
1522-1601 (Electronic)
ISSN-L
0161-7567
Statut éditorial
Publié
Date de publication
01/05/2022
Peer-reviewed
Oui
Volume
132
Numéro
5
Pages
1179-1189
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Oxygen uptake (V̇o <sub>2</sub> ) at exercise onset is determined in part by acceleration of pulmonary blood flow ([Formula: see text]). Impairments in the [Formula: see text] response can decrease exercise tolerance. Prior research has shown that voluntary respiratory maneuvers can augment venous return, but the corollary impacts on cardiac function, [Formula: see text] and early-exercise V̇o <sub>2</sub> remain uncertain. We examined 1) the cardiovascular effects of three distinct respiratory maneuvers (abdominal, AB; rib cage, RC; and deep breathing, DB) under resting conditions in healthy subjects (Protocol 1, n = 13), and 2) the impact of pre-exercise DB on pulmonary O <sub>2</sub> transfer during initiation of moderate-intensity exercise (Protocol 2, n = 8). In Protocol 1, echocardiographic analysis showed increased right ventricular (RV) cardiac output and left ventricular (LV) cardiac output (RVCO and LVCO, respectively), following AB (by +23 ± 13 and +18 ± 15%, respectively, P < 0.05), RC (+23 ± 16; +14 ± 15%, P < 0.05), and DB (+27 ± 21; +23 ± 14%, P < 0.05). In Protocol 2, DB performed for 12 breaths produced a pre-exercise increase in V̇o <sub>2</sub> (+801 ± 254 mL·min <sup>-1</sup> over ∼6 s), presumably from increased [Formula: see text], followed by a reduction in pulmonary O <sub>2</sub> transfer during early phase exercise (first 20 s) compared with the control condition (149 ± 51 vs. 233 ± 65 mL, P < 0.05). We conclude that 1) respiratory maneuvers enhance RVCO and LVCO in healthy subjects under resting conditions, 2) AB, RC, and DB have similar effects on RVCO and LVCO, and 3) DB can increase [Formula: see text] before exercise onset. These findings suggest that pre-exercise respiratory maneuvers may represent a promising strategy to prime V̇o <sub>2</sub> kinetics and thereby to potentially improve exercise tolerance in patients with impaired cardiac function.NEW & NOTEWORTHY We demonstrate that different breathing maneuvers can augment both right and left-sided cardiac output in healthy subjects. These maneuvers, when performed immediately before exercise, result in a pre-exercise "cardiodynamic" increase in oxygen uptake (V̇o <sub>2</sub> ) associated with a subsequent reduction in the "cardiodynamic" V̇o <sub>2</sub> normally seen during early exercise. We conclude that pre-exercise breathing maneuvers are a plausible tool worthy of additional study to prime V̇o <sub>2</sub> kinetics and improve exercise tolerance in patients with cardiovascular disease.
Mots-clé
Exercise/physiology, Exercise Tolerance, Humans, Oxygen, Oxygen Consumption/physiology, Respiratory Rate, cardiac function, exercise, oxygen uptake kinetics, respiratory pump, venous return
Pubmed
Création de la notice
21/03/2022 9:21
Dernière modification de la notice
20/07/2022 6:13
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