Uveitis and juvenile idiopathic arthritis: A cohort study.

Détails

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Etat: Public
Version: Final published version
Licence: Non spécifiée
ID Serval
serval:BIB_DEC2E5D709C6
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Uveitis and juvenile idiopathic arthritis: A cohort study.
Périodique
Clinical Ophthalmology (auckland, N.z.)
Auteur⸱e⸱s
BenEzra D., Cohen E., Behar-Cohen F.
ISSN
1177-5467 (Print)
ISSN-L
1177-5467
Statut éditorial
Publié
Date de publication
2007
Peer-reviewed
Oui
Volume
1
Numéro
4
Pages
513-518
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
OBJECTIVE: Assess the incidence of intraocular inflammation (uveitis) and ocular complications in children with various types of JIA in a single cohort of patients.
PATIENTS: Included are 172 children (35 boys and 137 girls) diagnosed with JIA. All underwent thorough initial ophthalmologic examination and were followed for a minimum of 3 years.
RESULTS: Of 172 children with JIA, 152 (88.4%) presented with arthritis. Uveitis was detected in 14 of the152 children (9.2%) during the first ophthalmic examination. In 17 additional patients of this group (11.2%), uveitis developed during the follow up period of up to 15 years. Twenty children out of the total of 172 (11.6%) presented initially with uveitis. In children developing uveitis before or along with arthritic manifestations, the ocular disease was chronic with a high rate of secondary complications (band keratopathy, glaucoma, posterior synechiae and cataract). In all affected eyes the initial ocular inflammation was typically confined to the anterior segment. On longer follow up however, most children developed binocular disease and posterior segment involvement. Dense cataract and amblyopia were the major cause of severe visual disabilities.
CONCLUSION: Pauciarticular JIA is associated with intraocular inflammation (uveitis) early during the arthritic disease course. The ocular disease course is unpredictable. Therefore education of parents regarding its signs and symptoms is of utmost importance. To preserve functional vision, secondary ocular complications and amblyopia should be avoided.
Pubmed
Création de la notice
27/08/2013 14:33
Dernière modification de la notice
20/08/2019 16:03
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