A comparison between ¹⁸F-FDG PET/CT imaging and biological and radiological findings in restaging of hepatoblastoma patients.

Détails

ID Serval
serval:BIB_DDE179A53BE7
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
A comparison between ¹⁸F-FDG PET/CT imaging and biological and radiological findings in restaging of hepatoblastoma patients.
Périodique
BioMed research international
Auteur(s)
Cistaro A., Treglia G., Pagano M., Fania P., Bova V., Basso M.E., Fagioli F., Ficola U., Quartuccio N.
ISSN
2314-6141 (Electronic)
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
2013
Pages
709037
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Résumé
In this study we retrospectively evaluated if ¹⁸F-FDG-PET/CT provided incremental diagnostic information over CI in a group of hepatoblastoma patients performing restaging.
Nine patients (mean age: 5.9 years; range: 3.1-12 years) surgically treated for hepatoblastoma were followed up by clinical examination, serum α-FP monitoring, and US. CI (CT or MRI) and PET/CT were performed in case of suspicion of relapse. Fine-needle aspiration biopsies (FNAB) were carried out for final confirmation if the results of CI, PET/CT, and/or α-FP levels were suggestive of relapse. PET/CT and CI findings were analyzed for comparison purposes, using FNAB as reference standard.
α-FP level was suggestive of disease recurrence in 8/9 patients. Biopsy was performed in 8/9 cases. CI and PET/CT resulted to be concordant in 5/9 patients (CI identified recurrence of disease, but ¹⁸F-FDG-PET/CT provided a better definition of disease extent); in 4/9 cases, CI diagnostic information resulted in negative findings, whereas PET/CT correctly detected recurrence of disease. ¹⁸F-FDG-PET/CT showed an agreement of 100% (8/8) with FNAB results.
¹⁸F-FDG-PET/CT scan seems to better assess HB patients with respect to CI and may provide incremental diagnostic value in the restaging of this group of patients.

Mots-clé
Child, Child, Preschool, Fluorodeoxyglucose F18, Hepatoblastoma/diagnostic imaging, Hepatoblastoma/pathology, Humans, Liver Neoplasms/diagnostic imaging, Liver Neoplasms/pathology, Magnetic Resonance Imaging, Multimodal Imaging, Neoplasm Staging, Positron-Emission Tomography, Tomography, X-Ray Computed
Pubmed
Web of science
Open Access
Oui
Création de la notice
20/08/2017 20:14
Dernière modification de la notice
20/08/2019 17:02
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