Impact of a bicarbonated saline solution on early resuscitation after major burns
Détails
ID Serval
serval:BIB_DDA6126D3A13
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Impact of a bicarbonated saline solution on early resuscitation after major burns
Périodique
Intensive Care Medicine
ISSN
0342-4642 (Print)
Statut éditorial
Publié
Date de publication
09/2000
Volume
26
Numéro
9
Pages
1382-5
Notes
Comparative Study
Journal Article --- Old month value: Sep
Journal Article --- Old month value: Sep
Résumé
OBJECTIVE: The study aimed at assessing the impact of the introduction of a bicarbonated saline solution on total fluid load, weight gain and acid base status during acute burn resuscitation. DESIGN: Based on a retrospective patient record review. SETTING: Burn care centre of a surgical ICU in a tertiary university hospital. PATIENTS: Two groups of adult patients (20/20), with thermal burns of 25% or more body surface area were studied. INTERVENTION: Modification of the resuscitation fluid composition from lactated Ringer's solution (LR: Na 132 mmol/l, Cl 112 mmol/l, 263 mosm/l), to bicarbonated 0.9% saline (BS: Na 180 mmol/l, Cl 154 mmol/l, 340 mosm/l) METHODS: Age, weight, burn size and depth, inhalation injury, fluid intakes over 48 h post-injury, plasma sodium, chloride, creatinine, albumin levels, blood gases and ventilation support were recorded. RESULTS: The demographic characteristics of the patients (41 +/- 16 years) in the two groups were not different, with severe burns involving 44 +/- 17% body surface area. While the total fluid volumes administered did not differ, BS was associated with lower plasma pH, base excess and bicarbonate levels for 24 h and with hyperchloraemia. Clinical evolution did not differ. CONCLUSIONS: Using bicarbonated saline solution for resuscitation causes a transient hyperchloraemic dilutional acidosis compared with LR, and has no other detectable clinical impact over the first 10 days after severe burn injury.
Mots-clé
Adult
Analysis of Variance
Burns/*therapy
Chi-Square Distribution
Female
Fluid Therapy/*methods
Hetastarch/therapeutic use
Humans
Intensive Care/methods
Isotonic Solutions/*therapeutic use
Male
Plasma Substitutes/therapeutic use
Resuscitation/*methods
Retrospective Studies
Saline Solution, Hypertonic/*therapeutic use
Sodium Bicarbonate/*therapeutic use
Treatment Outcome
Pubmed
Web of science
Création de la notice
24/01/2008 18:04
Dernière modification de la notice
20/08/2019 17:02