Regulation of antibiotic production in root-colonizing Peudomonas spp. and relevance for biological control of plant disease.

Détails

ID Serval
serval:BIB_DBC3913B856B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Regulation of antibiotic production in root-colonizing Peudomonas spp. and relevance for biological control of plant disease.
Périodique
Annual Review of Phytopathology
Auteur(s)
Haas D., Keel C.
ISSN
0066-4286[print], 0066-4286[linking]
Statut éditorial
Publié
Date de publication
2003
Volume
41
Pages
117-153
Langue
anglais
Résumé
Certain strains of fluorescent pseudomonads are important biological components of agricultural soils that are suppressive to diseases caused by pathogenic fungi on crop plants. The biocontrol abilities of such strains depend essentially on aggressive root colonization, induction of systemic resistance in the plant, and the production of diffusible or volatile antifungal antibiotics. Evidence that these compounds are produced in situ is based on their chemical extraction from the rhizosphere and on the expression of antibiotic biosynthetic genes in the producer strains colonizing plant roots. Well-characterized antibiotics with biocontrol properties include phenazines, 2,4-diacetylphloroglucinol, pyoluteorin, pyrrolnitrin, lipopeptides, and hydrogen cyanide. In vitro, optimal production of these compounds occurs at high cell densities and during conditions of restricted growth, involving (i) a number of transcriptional regulators, which are mostly pathway-specific, and (ii) the GacS/GacA two-component system, which globally exerts a positive effect on the production of extracellular metabolites at a posttranscriptional level. Small untranslated RNAs have important roles in the GacS/GacA signal transduction pathway. One challenge in future biocontrol research involves development of new strategies to overcome the broad toxicity and lack of antifungal specificity displayed by most biocontrol antibiotics studied so far.
Mots-clé
Anti-Bacterial Agents/biosynthesis, Pest Control, Biological, Plant Roots/microbiology, Pseudomonas/metabolism, RNA Processing, Post-Transcriptional, Transcription, Genetic
Pubmed
Web of science
Création de la notice
24/01/2008 13:51
Dernière modification de la notice
20/08/2019 16:00
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