Indocyanine green angiography in Fundus flavimaculatus

Détails

ID Serval
serval:BIB_DB27D689A810
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Indocyanine green angiography in Fundus flavimaculatus
Périodique
Ophthalmologica
Auteur(s)
Schwoerer  J., Secretan  M., Zografos  L., Piguet  B.
ISSN
0030-3755 (Print)
Statut éditorial
Publié
Date de publication
2000
Volume
214
Numéro
4
Pages
240-5
Notes
Comparative Study
Journal Article
Résumé
PURPOSE: To describe the characteristic findings of fundus flavimaculatus (Stargardt disease) as seen on indocyanine green angiography. METHODS: Twelve eyes of 6 consecutive patients with fundus flavimaculatus were studied by fundus color photographs, fluorescein angiography and indocyanine green angiography. RESULTS: Indocyanine green angiography allowed visualization of small, clearly demarcated areas in which hypofluorescence increased over time, leading eventually to a large reticular pattern with small areas of normal-appearing choroid encircled by a well-defined network of hypofluorescent curvilinear lesions. These hypofluorescent flecks were present in all 12 eyes but corresponded only partially to the yellow flecks visible on biomicroscopy of the fundus. The peripapillary area was well preserved on indocyanine green angiography and the periphery did not show any visible abnormalities. CONCLUSIONS: The hypofluorescent curvilinear areas visualized on indocyanine green angiography form a reticular pattern that is similar to the polygonal shape of the watershed zones between terminal choroidal arterioles, which supply the choriocapillaris. These dark areas may reflect choriocapillaris defects secondary to lysis of lipofuscin-engorged retinal pigment epithelial cells. The typical lesions of fundus flavimaculatus thus seem to be situated in areas of least vascular supply. Their absence in the peripapillary area, which benefits from anastomotic vascular connections, would support this hypothesis.
Mots-clé
Adult Diagnosis, Differential *Fluorescein Angiography Fluorescent Dyes/administration & dosage/*diagnostic use *Fundus Oculi Humans Indocyanine Green/administration & dosage/*diagnostic use Injections, Intravenous Macular Degeneration/*diagnosis
Pubmed
Web of science
Création de la notice
28/01/2008 13:10
Dernière modification de la notice
20/08/2019 16:00
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