Autoimmune retinal dysfunction in sarcoid chorioretinopathy.
Détails
ID Serval
serval:BIB_D7DC2C0757C2
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Autoimmune retinal dysfunction in sarcoid chorioretinopathy.
Périodique
Klinische Monatsblätter für Augenheilkunde
ISSN
0023-2165 (Print)
ISSN-L
0023-2165
Statut éditorial
Publié
Date de publication
05/2006
Peer-reviewed
Oui
Volume
223
Numéro
5
Pages
428-430
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
BACKGROUND: Visual loss, photophobia and night-blindness in a middle-aged patient with a previous history of cancer are highly suggestive of cancer-associated retinopathy.
HISTORY AND SIGNS: A 63-year-old man complained of slowly progressive bilateral visual loss, photophobia and night-blindness. His past medical history was remarkable for surgical and medical treatment of a carcinoma of the base of his tongue nine years earlier. Visual acuity was 0.3 RE and 0.15 LE, with constricted visual field in both eyes. Ocular examination and fluorescein angiography were non-relevant. Electroretinography revealed diffuse cone and rod dysfunction. ICG angiography showed multiple small widespread hyperfluorescent spots. A chest CT scan revealed multiple focal lesions which were biopsied. Histological diagnosis was sarcoidosis.
THERAPY AND OUTCOME: Upon systemic steroid therapy, visual function gradually improved, and ICG anomalies disappeared. Vision recovered to 1.0 RE and 0.8 LE with normal visual field in both eyes.
CONCLUSION: Sarcoidosis may present as an autoimmune retinal dysfunction with photophobia and night blindness as the presenting symptoms.
HISTORY AND SIGNS: A 63-year-old man complained of slowly progressive bilateral visual loss, photophobia and night-blindness. His past medical history was remarkable for surgical and medical treatment of a carcinoma of the base of his tongue nine years earlier. Visual acuity was 0.3 RE and 0.15 LE, with constricted visual field in both eyes. Ocular examination and fluorescein angiography were non-relevant. Electroretinography revealed diffuse cone and rod dysfunction. ICG angiography showed multiple small widespread hyperfluorescent spots. A chest CT scan revealed multiple focal lesions which were biopsied. Histological diagnosis was sarcoidosis.
THERAPY AND OUTCOME: Upon systemic steroid therapy, visual function gradually improved, and ICG anomalies disappeared. Vision recovered to 1.0 RE and 0.8 LE with normal visual field in both eyes.
CONCLUSION: Sarcoidosis may present as an autoimmune retinal dysfunction with photophobia and night blindness as the presenting symptoms.
Mots-clé
Autoimmune Diseases/diagnosis, Autoimmune Diseases/therapy, Choroid Diseases/diagnosis, Choroid Diseases/therapy, Humans, Male, Middle Aged, Night Blindness/etiology, Night Blindness/prevention & control, Photophobia/etiology, Photophobia/prevention & control, Retinal Diseases/diagnosis, Retinal Diseases/immunology, Sarcoidosis/diagnosis, Sarcoidosis/therapy
Pubmed
Web of science
Création de la notice
28/01/2008 13:37
Dernière modification de la notice
20/08/2019 16:57
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