Regional cerebral blood flow and oxygen metabolism in dementia due to vascular disease.

Détails

ID Serval
serval:BIB_D5CCF0AFD093
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Regional cerebral blood flow and oxygen metabolism in dementia due to vascular disease.
Périodique
Gerontology
Auteur⸱e⸱s
Gibbs J.M., Frackowiak R.S., Legg N.J.
ISSN
0304-324X (Print)
ISSN-L
0304-324X
Statut éditorial
Publié
Date de publication
1986
Volume
32 Suppl 1
Pages
84-88
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
Regional cerebral blood flow (CBF), oxygen utilisation (CMRO2) and fractional oxygen extraction (OER) were measured by positron emission tomography in patients with multi-infarct dementia. A matched reduction of both CBF and CMRO2 in the majority of patients indicated that in general, reduced cerebral perfusion in this condition is appropriate for the reduced metabolic demands of a damaged brain. Only in a very small minority of patients with dementia associated with bilateral carotid artery occlusion was CBF inappropriately low and OER raised. In these exceptional cases with critical cerebral perfusion, surgical measures to increase CBF could theoretically arrest or slow down the progress of dementia.
Mots-clé
Brain/blood supply, Brain/physiopathology, Dementia/physiopathology, Humans, Oxygen Consumption, Regional Blood Flow
Pubmed
Web of science
Création de la notice
08/10/2011 15:14
Dernière modification de la notice
20/08/2019 15:55
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