The role of nuclear medicine in the diagnosis of spondylodiscitis.

Détails

ID Serval
serval:BIB_D4F7401BF8FB
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
The role of nuclear medicine in the diagnosis of spondylodiscitis.
Périodique
European review for medical and pharmacological sciences
Auteur(s)
Treglia G., Focacci C., Caldarella C., Mattoli M.V., Salsano M., Taralli S., Giordano A.
ISSN
1128-3602 (Print)
ISSN-L
1128-3602
Statut éditorial
Publié
Date de publication
04/2012
Peer-reviewed
Oui
Volume
16 Suppl 2
Pages
20-25
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
The diagnosis of spondylodiscitis can be difficult, because the patients history, subjective symptoms and physical findings are often inconclusive, particularly in the early stages.
To perform an overview on the role of nuclear medicine procedures with single photon emission tomography (SPET) and positron emission tomography (PET) tracers in the diagnosis of spondylodiscitis.
A literature review about bone scintigraphy, Gallium-67-citrate scintigraphy, labeled leukocytes scintigraphy and PET was performed. Main findings of the literature were reported.
Bone scintigraphy is a sensitive and widely available nuclear medicine technique, but it is characterized by low specificity. Gallium-67-citrate scintigraphy is often used as a complement to bone scintigraphy to enhance the specificity of the study and to detect extra-osseous sites of infection. Labeled leukocytes scintigraphy is not a useful method in the diagnosis of spondylodiscitis. Fluorine-18-fluorodeoxyglucose positron emission tomography is a sensitive method and could potentially be useful in the diagnosis of spondylodiscitis and in the evaluation of treatment response. Nevertheless, scientific literature about this topic is still limited.
Overall, nuclear medicine procedures play a useful role in the diagnosis of spondylodiscitis identifying functional abnormalities which precede morphological changes. Therefore, nuclear medicine procedures may complement or integrate morphological imaging findings in patients with suspected spondylodiscitis.

Mots-clé
Adult, Discitis/diagnostic imaging, Female, Humans, Intervertebral Disc/diagnostic imaging, Male, Middle Aged, Osteomyelitis/diagnostic imaging, Positron-Emission Tomography, Predictive Value of Tests, Radiopharmaceuticals, Tomography, Emission-Computed, Single-Photon
Pubmed
Web of science
Création de la notice
20/08/2017 21:57
Dernière modification de la notice
20/08/2019 16:54
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