The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation

Détails

ID Serval
serval:BIB_D33ADA552B0D
Type
Autre: (aucun autre type ne convient)
Collection
Publications
Institution
Titre
The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation
Auteur⸱e⸱s
Kosch Tiffany A., Torres-Sánchez María, Liedtke H. Christoph, Summers Kyle, Yun Maximina H., Crawford Andrew J., Maddock Simon T., Ahammed Md. Sabbir, Araújo Victor L. N., Bertola Lorenzo V., Bucciarelli Gary, Carné Albert, Carneiro Céline M., Chan Kin O., Chen Ying, Crottini Angelica, da Silva Jessica M., Denton Robert D., Dittrich Carolin, Themudo Gonçalo Espregueira, Farquharson Katherine A., Forsdick Natalie J., Gilbert Edward, Jing Che, Katzenback Barbara A., Kotharambath Ramachandran, Levis Nicholas A., Márquez Roberto, Mazepa Glib, Mulder Kevin P., Müller Hendrik, O'Connell Mary J., Orozco-terWengel Pablo, Palomar Gemma, Petzold Alice, Pfennig David W., Pfennig Karin S., Reichert Michael S., Robert Jacques, Scherz Mark D., Siu-Ting Karen, Snead Anthony A, Stöck Matthias, Stuckert Adam M. M., Stynoski Jennifer L., Tarvin Rebecca D., Wollenberg Valero Katherina C.
ISSN
2692-8205 (Electronic)
ISSN-L
2692-8205
Date de publication
01/07/2024
Langue
anglais
Résumé
Amphibians represent a diverse group of tetrapods, marked by deep divergence times between their three systematic orders and families. Studying amphibian biology through the genomics lens increases our understanding of the features of this animal class and that of other terrestrial vertebrates. The need for amphibian genomics resources is more urgent than ever due to the increasing threats to this group. Amphibians are one of the most imperiled taxonomic groups, with approximately 41% of species threatened with extinction due to habitat loss, changes in land use patterns, disease, climate change, and their synergistic effects. Amphibian genomics resources have provided a better understanding of ontogenetic diversity, tissue regeneration, diverse life history and reproductive modes, antipredator strategies, and resilience and adaptive responses. They also serve as critical models for understanding widespread genomic characteristics, including evolutionary genome expansions and contractions given they have the largest range in genome sizes of any animal taxon and multiple mechanisms of genetic sex determination. Despite these features, genome sequencing of amphibians has significantly lagged behind that of other vertebrates, primarily due to the challenges of assembling their large, repeat-rich genomes and the relative lack of societal support. The advent of long-read sequencing technologies, along with computational techniques that enhance scaffolding capabilities and streamline computational workload is now enabling the ability to overcome some of these challenges. To promote and accelerate the production and use of amphibian genomics research through international coordination and collaboration, we launched the Amphibian Genomics Consortium (AGC) in early 2023. This burgeoning community already has more than 282 members from 41 countries (6 in Africa, 131 in the Americas, 27 in Asia, 29 in Australasia, and 89 in Europe). The AGC aims to leverage the diverse capabilities of its members to advance genomic resources for amphibians and bridge the implementation gap between biologists, bioinformaticians, and conservation practitioners. Here we evaluate the state of the field of amphibian genomics, highlight previous studies, present challenges to overcome, and outline how the AGC can enable amphibian genomics research to "leap" to the next level.
Pubmed
Création de la notice
24/07/2024 9:10
Dernière modification de la notice
25/07/2024 5:56
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