Administration orale d'un antiprogesterone (Mifepristone, RU 486) pour la preparation du col uterin a l'interruption de grossesse au cours du premier trimestre. [Oral administration of an antiprogesterone (Mifepristone, RU 486) for preparing the cervix uteri for pregnancy interruption during the first trimester]

Détails

ID Serval
serval:BIB_D3164F0E059B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Administration orale d'un antiprogesterone (Mifepristone, RU 486) pour la preparation du col uterin a l'interruption de grossesse au cours du premier trimestre. [Oral administration of an antiprogesterone (Mifepristone, RU 486) for preparing the cervix uteri for pregnancy interruption during the first trimester]
Périodique
Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
Auteur(s)
De Grandi  P., Giudici  G.
ISSN
0368-2315 (Print)
Statut éditorial
Publié
Date de publication
1989
Volume
18
Numéro
6
Pages
801-8
Notes
Clinical Trial
English Abstract
Journal Article
Randomized Controlled Trial
Résumé
Oral, double-blind administration in 2 groups of 20 patients each of a placebo versus 100mg Mifepriston given morning and evening for 48 hours, shows that this progesterone antagonist exerts a softening and dilating effect on the uterine cervix. This effect facilitates the instrumental dilation required for termination of pregnancy on the first trimester. While effective and free of side effects, this technic for cervical preparation has the further advantage of being nearly painless and thus may be applied to out-patients.
Mots-clé
Abortion, Induced/*instrumentation Administration, Oral Adult Cervix Uteri Dilatation Double-Blind Method Drug Evaluation Female Humans *Mifepristone Pregnancy Pregnancy Trimester, First Randomized Controlled Trials
Pubmed
Création de la notice
25/01/2008 15:40
Dernière modification de la notice
20/08/2019 15:53
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