What treatment should we use if drugs fail for OAB; and, what really works after drugs?

Détails

ID Serval
serval:BIB_D223F94BD485
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
What treatment should we use if drugs fail for OAB; and, what really works after drugs?
Périodique
Neurourology and Urodynamics
Auteur⸱e⸱s
Bosch J.L., Kelleher C., van Kerrebroeck P.E., Schurch B.
ISSN
1520-6777 (Electronic)
ISSN-L
0733-2467
Statut éditorial
Publié
Date de publication
2010
Volume
29
Numéro
4
Pages
658-661
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
AIMS: To determine (using structured brain storm sessions), which treatments should be used if drugs fail for OAB and to determine priority research questions in relation to this issue.
METHODS: A frame work for discussion was prepared by the chairman of the session; this included a brief summary of the currently existing evidence. Several experts had been asked to prepare a presentation of their personal treatment algorithm and to identify the [lack of] evidence for such an algorithm. These presentations were summarized by the chairman. Next, this summary was discussed with a large group of experts and opinion leaders and audio-recorded. The proceedings of this process are the basis for this manuscript.
RESULTS: The structured sessions resulted in detailed statements about: possible reasons for failure of conservative treatment, the evaluation of outcomes of RCT's, the use of botulinum toxin A in refractory OAB patients, the relative place of neuromodulation or sacral nerve stimulation and botulinum toxin A in the treatment of refractory OAB.
CONCLUSIONS: A list of 10 unanswered questions and research topics was compiled. Additionally, 5 top priority research topics were identified.
Mots-clé
Botulinum Toxins, Type A/therapeutic use, Female, Humans, Lumbosacral Plexus/physiopathology, Neuromuscular Agents/therapeutic use, Treatment Failure, Urinary Bladder/drug effects, Urinary Bladder/innervation, Urinary Bladder, Overactive/drug therapy, Urinary Bladder, Overactive/physiopathology, Urinary Incontinence/drug therapy, Urinary Incontinence/physiopathology
Pubmed
Web of science
Création de la notice
05/11/2014 12:12
Dernière modification de la notice
20/08/2019 15:52
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