Fructose Metabolism from a Functional Perspective: Implications for Athletes.

Détails

ID Serval
serval:BIB_D213029A0D19
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Fructose Metabolism from a Functional Perspective: Implications for Athletes.
Périodique
Sports medicine
Auteur(s)
Tappy L., Rosset R.
ISSN
1179-2035 (Electronic)
ISSN-L
0112-1642
Statut éditorial
Publié
Date de publication
03/2017
Peer-reviewed
Oui
Volume
47
Numéro
Suppl 1
Pages
23-32
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Substantial amounts of fructose are present in our diet. Unlike glucose, this hexose cannot be metabolized by most cells and has first to be converted into glucose, lactate or fatty acids by enterocytes, hepatocytes and kidney proximal tubule cells, which all express specific fructose-metabolizing enzymes. This particular metabolism may then be detrimental in resting, sedentary subjects; however, this may also present some advantages for athletes. First, since fructose and glucose are absorbed through distinct, saturable gut transporters, co-ingestion of glucose and fructose may increase total carbohydrate absorption and oxidation. Second, fructose is largely metabolized into glucose and lactate, resulting in a net local lactate release from splanchnic organs (mostly the liver). This 'reverse Cori cycle' may be advantageous by providing lactate as an additional energy substrate to the working muscle. Following exercise, co-ingestion of glucose and fructose mutually enhance their own absorption and storage.
Mots-clé
Athletes, Athletic Performance, Carbohydrate Metabolism/physiology, Dietary Carbohydrates/metabolism, Exercise/physiology, Fructose/metabolism, Glucose, Humans, Sports Nutritional Physiological Phenomena
Pubmed
Web of science
Création de la notice
24/03/2017 10:45
Dernière modification de la notice
20/08/2019 15:52
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