Delayed-Phase Cone-Beam CT Improves Detectability of Intrahepatic Cholangiocarcinoma During Conventional Transarterial Chemoembolization.

Détails

ID Serval
serval:BIB_D17FB7385C5D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Delayed-Phase Cone-Beam CT Improves Detectability of Intrahepatic Cholangiocarcinoma During Conventional Transarterial Chemoembolization.
Périodique
Cardiovascular and Interventional Radiology
Auteur(s)
Schernthaner R.E., Lin M., Duran R., Chapiro J., Wang Z., Geschwind J.F.
ISSN
1432-086X (Electronic)
ISSN-L
0174-1551
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
38
Numéro
4
Pages
929-936
Langue
anglais
Résumé
PURPOSE: To evaluate the detectability of intrahepatic cholangiocarcinoma (ICC) on dual-phase cone-beam CT (DPCBCT) during conventional transarterial chemoembolization (cTACE) compared to that of digital subtraction angiography (DSA) with respect to pre-procedure contrast-enhanced magnetic resonance imaging (CE-MRI) of the liver.
METHODS: This retrospective study included 17 consecutive patients (10 male, mean age 64) with ICC who underwent pre-procedure CE-MRI of the liver, and DSA and DPCBCT (early-arterial phase (EAP) and delayed-arterial phase (DAP)) just before cTACE. The visibility of each ICC lesion was graded by two radiologists on a three-rank scale (complete, partial, and none) on DPCBCT and DSA images, and then compared to pre-procedure CE-MRI.
RESULTS: Of 61 ICC lesions, only 45.9% were depicted by DSA, whereas EAP- and DAP-CBCT yielded a significantly higher detectability rate of 73.8% and 93.4%, respectively (p < 0.01). Out of the 33 lesions missed on DSA, 18 (54.5%) and 30 (90.9%) were revealed on EAP- and DAP-CBCT images, respectively. DSA depicted only one lesion that was missed by DPCBCT due to streak artifacts caused by a prosthetic mitral valve. DAP-CBCT identified significantly more lesions than EAP-CBCT (p < 0.01). Conversely, EAP-CBCT did not detect lesions missed by DAP-CBCT. For complete lesion visibility, DAP-CBCT yielded significantly higher detectability (78.7%) compared to EAP (31.1%) and DSA (21.3%) (p < 0.01).
CONCLUSION: DPCBCT, and especially the DAP-CBCT, significantly improved the detectability of ICC lesions during cTACE compared to DSA. We recommend the routine use of DAP-CBCT in patients with ICC for per-procedure detectability and treatment planning in the setting of TACE.
Mots-clé
Angiography, Digital Subtraction, Bile Duct Neoplasms/radiography, Bile Duct Neoplasms/therapy, Chemoembolization, Therapeutic, Cholangiocarcinoma/radiography, Cholangiocarcinoma/therapy, Cohort Studies, Cone-Beam Computed Tomography, Female, Humans, Liver/pathology, Liver/radiography, Magnetic Resonance Imaging, Male, Middle Aged, Observer Variation, Radiography, Interventional, Reproducibility of Results, Retrospective Studies
Pubmed
Web of science
Création de la notice
14/06/2016 9:22
Dernière modification de la notice
20/08/2019 15:51
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