SnapShot: FMRP mRNA targets and diseases.
Détails
ID Serval
serval:BIB_D142B10FEF34
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Lettre (letter): communication adressée à l'éditeur.
Collection
Publications
Institution
Titre
SnapShot: FMRP mRNA targets and diseases.
Périodique
Cell
ISSN
1097-4172 (Electronic)
ISSN-L
0092-8674
Statut éditorial
Publié
Date de publication
11/09/2014
Peer-reviewed
Oui
Volume
158
Numéro
6
Pages
1446-1446.e1
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
FMRP, or fragile X mental retardation protein is an RNA-binding protein. Mutations in the FMRP protein have been associated with neurological disease as have a number of its mRNA-binding targets. This SnapShot presents 40 bona fide FMRP targets for which mRNA binding and protein regulation have been robustly reported in mammals along with the diseases with which they have been associated.
Mots-clé
Animals, Brain Diseases/genetics, Brain Diseases/metabolism, Fragile X Mental Retardation Protein/metabolism, Humans, Mental Disorders/genetics, Mental Disorders/metabolism, Neoplasms/genetics, Neoplasms/metabolism, RNA, Messenger/metabolism
Pubmed
Web of science
Open Access
Oui
Création de la notice
29/10/2018 12:38
Dernière modification de la notice
20/08/2019 16:51
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