Surgical resection of medulla oblongata hemangioblastomas: outcome and complications.

Détails

ID Serval
serval:BIB_D0BFD95440C9
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Surgical resection of medulla oblongata hemangioblastomas: outcome and complications.
Périodique
Acta Neurochirurgica
Auteur⸱e⸱s
Giammattei L., Messerer M., Aghakhani N., David P., Herbrecht A., Richard S., Parker F.
ISSN
0942-0940 (Electronic)
ISSN-L
0001-6268
Statut éditorial
Publié
Date de publication
05/2016
Peer-reviewed
Oui
Volume
158
Numéro
7
Pages
1333-1341
Langue
anglais
Résumé
OBJECT: The purpose of this study was to analyze the surgical outcome and complications of a single-center series of medulla oblongata (MO) hemangioblastomas.
METHODS: We retrospectively reviewed the medical charts of all medulla oblongata hemangioblastomas operated on at our institution between 1996 and 2015. All patients had a pre- and postoperative MRI and a minimum follow-up of 6 months. Patients were scored according to the Karnofsky Performance Scale (KPS) and McCormick Scale at the moment of admission, discharge and the last follow-up.
RESULTS: Thirty-one surgical procedures were performed on 27 patients (16 females and 11 males). The mean age was 33 years, and 93 % of patients had von Hippel Lindau (VHL) disease. Three patients experienced very complicated postoperative courses, with one case ending in the death of the patient. Two patients required tracheostomy. According to McCormick's classification, 7 (23 %) of the 31 operations resulted in aggravation and 23 (74 %) in no change. Considering the seven patients with aggravation at discharge, four patients (60 %) returned to their preoperative status, one (14 %) improved but remained below his preoperative McCormick grade and two (29 %) did not improve. At last follow-up, KPS was ameliorated in 53 %, stable in 40 % and worsened in 7 % of cases.
CONCLUSION: Surgery of medulla oblongata hemangioblastomas is a challenging procedure characterized by an acceptable morbidity. Transient morbidity is not negligible even if the long-term outcome is in most cases favorable. A compromised neurological condition seems to be the best predictor of unfavorable outcome.
Pubmed
Création de la notice
31/05/2016 16:42
Dernière modification de la notice
20/08/2019 15:51
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