Helicobacter pylori- inflammation, immunity and vaccines

Détails

ID Serval
serval:BIB_D0389687D36E
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Helicobacter pylori- inflammation, immunity and vaccines
Périodique
Helicobacter
Auteur(s)
Michetti  P., Svennerholm  A. M.
ISSN
1083-4389 (Print)
Statut éditorial
Publié
Date de publication
2003
Volume
8 Suppl 1
Pages
31-5
Notes
Journal Article
Review
Résumé
The mechanisms by which Helicobacter pylori escape the host immune response remains an important topic. Regulatory T cells appear to play a role in the persistence of the infection and the control of tissue damage. In the thought that the host genetic background influences the cross-talk between pathogens and hosts, the impact of cytokine polymorphisms on the outcome of H. pylori has been further delineated in the review period. On the other hand, several additional genes of H. pylori have been shown to participate in the pro-inflammatory cytokine and chemokine response to the infection. Finally, progress has been achieved in vaccine development, with new vaccine delivery systems and routes of immunization tested in animal models and human volunteers.
Mots-clé
Animals *Bacterial Vaccines Helicobacter Infections/genetics/*immunology/*prevention & control Helicobacter pylori/*immunology Humans
Pubmed
Web of science
Création de la notice
25/01/2008 16:02
Dernière modification de la notice
20/08/2019 15:50
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