Detection of coronary artery disease in diabetic patients
Détails
ID Serval
serval:BIB_CF2B839EDD01
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Detection of coronary artery disease in diabetic patients
Périodique
Diabetologia
ISSN
0012-186X
Statut éditorial
Publié
Date de publication
06/1995
Volume
38
Numéro
6
Pages
726-31
Notes
95402618
0012-186x
Journal Article --- Old month value: Jun --- Old uritopublisher value: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7672497
0012-186x
Journal Article --- Old month value: Jun --- Old uritopublisher value: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7672497
Résumé
Coronary artery disease may be difficult to detect in diabetic patients. This study was designed to determine the specificity and sensitivity of three noninvasive tests. Accordingly, the results of 48-h ambulatory electrocardiogram (ECG) monitoring, maximal ECG exercise test, and intravenous dipyridamole myocardial thallium scintigraphy were compared in 59 middle-aged diabetic patients who were consecutively selected for suspected coronary artery disease. All patients also underwent coronary angiography, which was performed regardless of the results of the non-invasive tests. Twenty patients (34%) had significant coronary lesions, i.e. stenosis equal to or greater than 70%, and 16 of these 20 patients (80%) had double or triple vessel disease. Sensitivity and specificity were, respectively, 25% and 88% for ambulatory ECG monitoring, 75% and 77% for the exercise test and 80% and 87% for thallium myocardial scintigraphy. This observation strongly supports the use of non-invasive tests for the detection of coronary artery disease in those diabetic patients at high risk of such disease. As the exercise test is cheaper and more widely available than thallium myocardial scintigraphy it should be used as a first line examination. Dipyridamole myocardial scintigraphy may provide an alternative solution for those patients who cannot perform maximal exercise, or with atypical clinical presentation.
Mots-clé
Adult
Aged
Comparative Study
Coronary Disease/*diagnosis/physiopathology
Diabetes Mellitus, Insulin-Dependent/*physiopathology
Diabetes Mellitus, Non-Insulin-Dependent/*physiopathology
Diabetic Angiopathies/*diagnosis/physiopathology
Dipyridamole/diagnostic use
*Electrocardiography
Exercise Test
Female
Heart/radionuclide imaging
Human
Male
Middle Age
Predictive Value of Tests
Sensitivity and Specificity
Thallium Radioisotopes/diagnostic use
Pubmed
Web of science
Création de la notice
03/03/2008 16:16
Dernière modification de la notice
20/08/2019 16:49