Validation of MLC leaf open time calculation methods for PSQA in adaptive radiotherapy with tomotherapy units.

Détails

Ressource 1Télécharger: J Applied Clin Med Phys - 2024 - Nasrallah - Validation of MLC leaf open time calculation methods for PSQA in adaptive.pdf (1437.05 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_CEC8943C833B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Validation of MLC leaf open time calculation methods for PSQA in adaptive radiotherapy with tomotherapy units.
Périodique
Journal of applied clinical medical physics
Auteur⸱e⸱s
Nasrallah M., Bochud F., Tellapragada N., Bourhis J., Chao E., Casey D., Moeckli R.
ISSN
1526-9914 (Electronic)
ISSN-L
1526-9914
Statut éditorial
Publié
Date de publication
10/2024
Peer-reviewed
Oui
Volume
25
Numéro
10
Pages
e14478
Langue
anglais
Notes
Publication types: Journal Article ; Validation Study
Publication Status: ppublish
Résumé
Treatment delivery safety and accuracy are essential to control the disease and protect healthy tissues in radiation therapy. For usual treatment, a phantom-based patient specific quality assurance (PSQA) is performed to verify the delivery prior to the treatment. The emergence of adaptive radiation therapy (ART) adds new complexities to PSQA. In fact, organ at risks and target volume re-contouring as well as plan re-optimization and treatment delivery are performed with the patient immobilized on the treatment couch, making phantom-based pretreatment PSQA impractical. In this case, phantomless PSQA tools based on multileaf collimator (MLC) leaf open times (LOTs) verifications provide alternative approaches for the Radixact® treatment units. However, their validity is compromised by the lack of independent and reliable methods for calculating the LOT performed by the MLC during deliveries.
To provide independent and reliable methods of LOT calculation for the Radixact® treatment units.
Two methods for calculating the LOTs performed by the MLC during deliveries have been implemented. The first method uses the signal recorded by the build-in detector and the second method uses the signal recorded by optical sensors mounted on the MLC. To calibrate the methods to the ground truth, in-phantom ionization chamber LOT measurements have been conducted on a Radixact® treatment unit. The methods were validated by comparing LOT calculations with in-phantom ionization chamber LOT measurements performed on two Radixact® treatment units.
The study shows a good agreement between the two LOT calculation methods and the in-phantom ionization chamber measurements. There are no notable differences between the two methods and the same results were observed on the different treatment units.
The two implemented methods have the potential to be part of a PSQA solution for ART in tomotherapy.
Mots-clé
Humans, Radiotherapy Planning, Computer-Assisted/methods, Radiotherapy, Intensity-Modulated/methods, Radiotherapy Dosage, Phantoms, Imaging, Organs at Risk/radiation effects, Quality Assurance, Health Care/standards, Neoplasms/radiotherapy, Particle Accelerators/instrumentation, Algorithms, adaptive radiation therapy (ART), leaf open time (LOT), patient specific quality assurance (PSQA), tomotherapy
Pubmed
Web of science
Open Access
Oui
Création de la notice
09/08/2024 15:12
Dernière modification de la notice
26/10/2024 6:23
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