High flow nasal cannula improves breathing efficiency and ventilatory ratio in COPD patients recovering from an exacerbation.
Détails
ID Serval
serval:BIB_CE3FB0C83DD2
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Lettre (letter): communication adressée à l'éditeur.
Collection
Publications
Institution
Titre
High flow nasal cannula improves breathing efficiency and ventilatory ratio in COPD patients recovering from an exacerbation.
Périodique
Journal of critical care
ISSN
1557-8615 (Electronic)
ISSN-L
0883-9441
Statut éditorial
Publié
Date de publication
06/2022
Peer-reviewed
Oui
Volume
69
Pages
154023
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
High flow nasal cannula (HFNC) may improve CO <sub>2</sub> elimination by washing out CO <sub>2</sub> from the upper airways. This study aimed at assessing the effect of HFNC on minute ventilation and ventilatory ratio (VR), a surrogate of dead space, in patients hospitalized for acute hypercapnic COPD exacerbation.
Physiological study comparing HFNC at 40 L/min to low flow oxygen. Variations of tidal volume (VT) and minute ventilation between the two treatments were estimated from chest plethysmography. Respiratory rate (RR) and arterial blood gases were measured. Variations in VR were calculated. Data were compared using Wilcoxon tests.
Recordings performed in 10 patients. Minute ventilation was reduced with HFNC by -16.2 [-30.9-0.4] % (p = 0.049). VT was not different but RR was lower during HFNC. PaCO <sub>2</sub> was lower with HFNC compared to standard oxygen: 48.7 [46.4-58.1] vs 50.7 [48.4-57.5] mmHg (p = 0.020). VR decreased by -18.0 [-34.7 - -4.0] % (p = 0.020) with HFNC.
In patients recovering from acute COPD exacerbation, the use of HFNC reduced RR, minute ventilation, PaCO <sub>2</sub> and VR compared to standard oxygen. These changes are consistent with a decrease in physiologic dead space with HFNC.
Physiological study comparing HFNC at 40 L/min to low flow oxygen. Variations of tidal volume (VT) and minute ventilation between the two treatments were estimated from chest plethysmography. Respiratory rate (RR) and arterial blood gases were measured. Variations in VR were calculated. Data were compared using Wilcoxon tests.
Recordings performed in 10 patients. Minute ventilation was reduced with HFNC by -16.2 [-30.9-0.4] % (p = 0.049). VT was not different but RR was lower during HFNC. PaCO <sub>2</sub> was lower with HFNC compared to standard oxygen: 48.7 [46.4-58.1] vs 50.7 [48.4-57.5] mmHg (p = 0.020). VR decreased by -18.0 [-34.7 - -4.0] % (p = 0.020) with HFNC.
In patients recovering from acute COPD exacerbation, the use of HFNC reduced RR, minute ventilation, PaCO <sub>2</sub> and VR compared to standard oxygen. These changes are consistent with a decrease in physiologic dead space with HFNC.
Mots-clé
Cannula, Carbon Dioxide, Humans, Noninvasive Ventilation, Oxygen, Oxygen Inhalation Therapy, Pulmonary Disease, Chronic Obstructive/therapy, Respiratory Insufficiency/therapy
Pubmed
Web of science
Création de la notice
09/04/2022 18:21
Dernière modification de la notice
21/03/2023 6:47
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