CO2 and mechanical factors reduce blood flow in a collapsed lung lobe

Détails

ID Serval
serval:BIB_CDF49780921B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
CO2 and mechanical factors reduce blood flow in a collapsed lung lobe
Périodique
Journal of Applied Physiology
Auteur(s)
McFarlane  P. A., Gardaz  J. P., Sykes  M. K.
ISSN
0161-7567 (Print)
Statut éditorial
Publié
Date de publication
09/1984
Volume
57
Numéro
3
Pages
739-43
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Sep
Résumé
Left lower lobe-to-total blood flow ratio (Ql/QT) was measured with electromagnetic flow probes in anesthetized open-chest dogs. There was a 66% reduction in Ql/QT during lobar collapse, a 53% reduction during lobar ventilation hypoxia with pulmonary venous PO2 and PCO2 equal to mixed venous tensions, and a 45% reduction during a similar degree of ventilation hypoxia but with normal end-tidal PCO2. We concluded that the reduction in blood flow during lobar collapse is due predominantly to hypoxic vasoconstriction, but that this mechanism is augmented by the raised PCO2 and mechanical factors present during collapse.
Mots-clé
Animals Anoxia/physiopathology Atelectasis/*physiopathology Carbon Dioxide/*physiology Cardiac Output Dogs Hydrogen-Ion Concentration Lung/*blood supply *Pulmonary Circulation Pulmonary Gas Exchange Stress, Mechanical
Pubmed
Web of science
Création de la notice
28/01/2008 11:48
Dernière modification de la notice
20/08/2019 16:48
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