Ex vivo performance comparison of three percutaneous biopsy needle systems.

Détails

ID Serval
serval:BIB_CDB67CD727D0
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Ex vivo performance comparison of three percutaneous biopsy needle systems.
Périodique
European radiology
Auteur(s)
Krokidis M., Hungerbühler M., Hewer E., Heverhagen J., von Tengg-Kobligk H.
ISSN
1432-1084 (Electronic)
ISSN-L
0938-7994
Statut éditorial
Publié
Date de publication
08/2019
Peer-reviewed
Oui
Volume
29
Numéro
8
Pages
4044-4049
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
The aim of this study is to identify the micro-mechanical characteristics that define biopsy performance in normal ex vivo animal organs.
Three biopsy systems with differences of needle external diameter, tray height and effective tray length were assessed. Sampling was performed in porcine liver and kidneys with commercially labelled 14G, 16G and 18G, using 2-cm throw needle systems. Five samples were obtained per needle size and per organ, and the experiment was repeated twice for a total of 90 biopsy cores. Samples were analysed and compared in terms of macroscopic aspect, sample length, weight and tissue architecture.
The system with the longest effective needle tray (system A) has shown significant superiority (p < 0.001) versus the other systems regarding the mean weight of tissue obtained for all needle sizes. Furthermore, the 14G needle of system A has shown superiority regarding the number of portal spaces and the 16G regarding the length of kidney fragments obtained.
The outcomes obtained with the different biopsy systems were not equal. The micro-mechanical characteristic that appears to influence the quantity and quality of the obtained tissue is the effective needle tray length and not the needle external diameter or the needle tray height. This information should be taken into account in the future design of biopsy needle systems, particularly when potentially used in the assessment of biomarkers and the characterisation of tumour micro-environment.
• The amount of obtained tissue mass is not the same among percutaneous biopsy needle systems. • There are different micro-mechanical characteristics that condition the amount of obtained tissue. • The micro-mechanical characteristic that offers more tissue mass for the same calibre is the effective length of the needle tray.
Mots-clé
Animals, Biopsy, Large-Core Needle/instrumentation, Disease Models, Animal, Equipment Design, Kidney/pathology, Kidney Diseases/diagnosis, Liver/pathology, Liver Diseases/diagnosis, Swine, Biopsy, Kidney, Liver, Tissue
Pubmed
Web of science
Création de la notice
31/08/2020 13:02
Dernière modification de la notice
10/11/2020 7:26
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