Inflammatory and metabolic responses to high-fat meals with and without dairy products in men.

Détails

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Etat: Public
Version: Final published version
ID Serval
serval:BIB_CB425C7D3F87
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Inflammatory and metabolic responses to high-fat meals with and without dairy products in men.
Périodique
British Journal of Nutrition
Auteur(s)
Schmid A., Petry N., Walther B., Bütikofer U., Luginbühl W., Gille D., Chollet M., McTernan P.G., Gijs M.A., Vionnet N., Pralong F.P., Laederach K., Vergères G.
ISSN
1475-2662 (Electronic)
ISSN-L
0007-1145
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
113
Numéro
12
Pages
1853-1861
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
Postprandial inflammation is an important factor for human health since chronic low-grade inflammation is associated with chronic diseases. Dairy products have a weak but significant anti-inflammatory effect on postprandial inflammation. The objective of the present study was to compare the effect of a high-fat dairy meal (HFD meal), a high-fat non-dairy meal supplemented with milk (HFM meal) and a high-fat non-dairy control meal (HFC meal) on postprandial inflammatory and metabolic responses in healthy men. A cross-over study was conducted in nineteen male subjects. Blood samples were collected before and 1, 2, 4 and 6 h after consumption of the test meals. Plasma concentrations of insulin, glucose, total cholesterol, LDL-cholesterol, HDL-cholesterol, TAG and C-reactive protein (CRP) were measured at each time point. IL-6, TNF-α and endotoxin concentrations were assessed at baseline and endpoint (6 h). Time-dependent curves of these metabolic parameters were plotted, and the net incremental AUC were found to be significantly higher for TAG and lower for CRP after consumption of the HFM meal compared with the HFD meal; however, the HFM and HFD meals were not different from the HFC meal. Alterations in IL-6, TNF-α and endotoxin concentrations were not significantly different between the test meals. The results suggest that full-fat milk and dairy products (cheese and butter) have no significant impact on the inflammatory response to a high-fat meal.
Pubmed
Web of science
Open Access
Oui
Création de la notice
08/08/2015 15:20
Dernière modification de la notice
20/08/2019 15:46
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