The role of epilepsy in early language development in a child with a congenital lesion in the right hemisphere

Détails

ID Serval
serval:BIB_CB26A5E008C9
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
The role of epilepsy in early language development in a child with a congenital lesion in the right hemisphere
Périodique
Developmental Medicine and Child Neurology
Auteur⸱e⸱s
Mayor-Dubois C., Maeder-Ingvar M., Deonna T., Roulet-Perez E.
ISSN
0012-1622
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
50
Numéro
11
Pages
870-875
Langue
anglais
Résumé
Early epilepsy is known to worsen the developmental prognosis of young children with a congenital focal brain lesion, but its direct role is often very difficult to delineate from the other variables. This requires prolonged periods of follow-up with simultaneous serial electrophysiological and developmental assessments which are rarely obtained. We studied a male infant with a right prenatal infarct in the territory of the right middle cerebral artery resulting in a left spastic hemiparesis, and an epileptic disorder (infantile spasms with transient right hemihypsarrhythmia and focal seizures) from the age of 7 months until the age of 4 years. Pregnancy and delivery were normal. A dissociated delay of early language acquisition affecting mainly comprehension without any autistic features was documented. This delay was much more severe than usually expected in children with early focal lesions, and its evolution, with catch-up to normal, was correlated with the active phase of the epilepsy. We postulate that the epilepsy specifically amplified a pattern of delayed language emergence, mainly affecting lexical comprehension, reported in children with early right hemisphere damage.
Mots-clé
Anticonvulsants, Brain, Child, Cognition Disorders, Electroencephalography, Epilepsy, Functional Laterality, Humans, Infant, Language Development Disorders, Male, Neuropsychological Tests, Severity of Illness Index, Valproic Acid
Pubmed
Web of science
Open Access
Oui
Création de la notice
21/01/2009 15:28
Dernière modification de la notice
20/08/2019 15:46
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