Degradation pathway of pentachlorophenol by Mucor plumbeus involves phase II conjugation and oxidation-reduction reactions.

Détails

ID Serval
serval:BIB_CAE8F17DD5C2
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Degradation pathway of pentachlorophenol by Mucor plumbeus involves phase II conjugation and oxidation-reduction reactions.
Périodique
Journal of hazardous materials
Auteur(s)
Carvalho M.B., Tavares S., Medeiros J., Núñez O., Gallart-Ayala H., Leitão M.C., Galceran M.T., Hursthouse A., Pereira C.S.
ISSN
1873-3336 (Electronic)
ISSN-L
0304-3894
Statut éditorial
Publié
Date de publication
30/12/2011
Volume
198
Pages
133-142
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Environmental pollution by pentachlorophenol (PCP) is a critical concern worldwide and fungal bioremediation constitutes an elegant and environment-friendly solution. Mucorales from the Zygomycota phylum are often observed to be competitive in field conditions and Mucor plumbeus, in particular, can efficiently deplete PCP from media. The pathway for PCP degradation used by this fungus has not been investigated. In this study, PCP-derived metabolites were identified by liquid chromatography coupled with quadrupole time-of-flight mass spectrometry, including tetra- and tri-chlorohydroquinones and phase II-conjugated metabolites. Amongst the latter are the previously reported glucose, sulfate and ribose conjugates, and identified for the first time in fungi sulfate-glucose conjugates. A PCP transformation pathway for M. plumbeus is proposed, which excludes the involvement of cytochrome P-450 and extracellular ligninolytic enzymes.

Mots-clé
Biodegradation, Environmental, Biotransformation, Chromatography, Liquid, Environmental Pollutants/metabolism, Environmental Pollutants/pharmacokinetics, Mass Spectrometry, Mucor/metabolism, Oxidation-Reduction, Pentachlorophenol/metabolism, Pentachlorophenol/pharmacokinetics
Pubmed
Création de la notice
02/06/2017 13:31
Dernière modification de la notice
21/08/2019 5:34
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