Recent developments in target identification against hepatitis C virus

Détails

ID Serval
serval:BIB_CADC01DF220B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Recent developments in target identification against hepatitis C virus
Périodique
Expert Opinion on Therapeutic Targets
Auteur(s)
Brass  V., Blum  H. E., Moradpour  D.
ISSN
1744-7631 (Electronic)
Statut éditorial
Publié
Date de publication
08/2004
Volume
8
Numéro
4
Pages
295-307
Notes
Journal Article
Review --- Old month value: Aug
Résumé
Chronic hepatitis C is a leading cause of liver cirrhosis and hepatocellular carcinoma worldwide. Recent progress in the understanding of the molecular virology of hepatitis C has allowed the identification of novel antiviral targets. Moreover, in vitro and in vivo model systems have been developed that allow the systematic evaluation of new therapeutic strategies. Exciting results from proof-of-concept clinical studies have now been reported for a specific hepatitis C virus serine protease inhibitor. These and other novel antiviral strategies may complement existing therapeutic modalities in the future.
Mots-clé
Animals Antiviral Agents/*administration & dosage Drug Delivery Systems/*methods Hepacivirus/*drug effects/enzymology Hepatitis C, Chronic/*drug therapy/enzymology Humans Serine Proteinase Inhibitors/*administration & dosage
Pubmed
Web of science
Création de la notice
25/01/2008 16:06
Dernière modification de la notice
20/08/2019 15:45
Données d'usage