Glucocorticoid-induced long-term remission in primary cerebral lymphoma: case report and review of the literature.

Détails

ID Serval
serval:BIB_CA6702D3DB84
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Glucocorticoid-induced long-term remission in primary cerebral lymphoma: case report and review of the literature.
Périodique
Journal of Neuro-Oncology
Auteur(s)
Pirotte B., Levivier M., Goldman S., Brucher J.M., Brotchi J., Hildebrand J.
ISSN
0167-594X (Print)
ISSN-L
0167-594X
Statut éditorial
Publié
Date de publication
1997
Peer-reviewed
Oui
Volume
32
Numéro
1
Pages
63-69
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Résumé
We report a 25-year old immunocompetent woman with a high grade primary non-Hodgkin's lymphoma of the central nervous system (PNHL-CNS) in whom the administration of dexamethasone alone during three months produced a complete clinical and radiological response lasting over four years. If complete remission of PNHL-CNS induced by glucocorticoids are well known, the opportunity to observe glucocorticoid-induced remission for a long period of time without radio- and chemotherapy is rare. Only nine other cases of PNHL-CNS with complete remission induced by glucocorticoids lasting from 6 to 60 months, were found in the literature and are summarized here. Duration of glucocorticoids therapeutic effect in PNHL-CNS is probably underestimated. Glucocorticoids cannot be recommended as sole initial treatment for PNHL-CNS. However, we suggest standard therapies to be delayed in those patients responding completely to glucocorticoids where radio- and chemotherapy should be contraindicated (kidney, liver, bone marrow failure, pregnancy).
Mots-clé
Adult, Brain Neoplasms/drug therapy, Brain Neoplasms/pathology, Female, Glucocorticoids/therapeutic use, Humans, Lymphoma, Non-Hodgkin/drug therapy, Lymphoma, Non-Hodgkin/pathology, Magnetic Resonance Imaging, Pregnancy
Pubmed
Web of science
Création de la notice
20/01/2008 18:35
Dernière modification de la notice
20/08/2019 16:45
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