Nouvelles strategies therapeutiques dans le sepsis severe et le choc septique. [New therapeutic strategies in severe sepsis and septic shock]

Détails

ID Serval
serval:BIB_C9083C3A5B0A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Nouvelles strategies therapeutiques dans le sepsis severe et le choc septique. [New therapeutic strategies in severe sepsis and septic shock]
Périodique
Revue Médicale de la Suisse Romande
Auteur⸱e⸱s
Oddo  M., Schaller  M. D., Calandra  T., Liaudet  L.
ISSN
0035-3655 (Print)
Statut éditorial
Publié
Date de publication
06/2004
Volume
124
Numéro
6
Pages
329-32
Notes
English Abstract
Journal Article
Review --- Old month value: Jun
Résumé
Severe sepsis and septic shock are an important cause of mortality. Until recently, in spite of major progresses in our understanding of the pathogenic mechanisms of this syndrome, clinicians had only a limited therapeutic arsenal. Considerable efforts have been made in the past few years to develop novel therapeutic interventions to reduce mortality in sepsis. So far, five specific therapies have proven their efficacy to achieve such goal in large randomised controlled trials: early goal-directed therapy, recombinant activated protein C, moderate doses of steroids, low tidal volume ventilation in acute respiratory distress syndrome and intensive insulin therapy to control hyperglycemia. This review will focus on these recently acquired therapeutic modalities, that are presently available to clinicians for the treatment of severe sepsis and septic shock.
Mots-clé
Humans Resuscitation Sepsis/mortality/*therapy Severity of Illness Index Shock, Septic/mortality/*therapy
Pubmed
Création de la notice
25/01/2008 14:28
Dernière modification de la notice
20/08/2019 16:44
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