Respiratory effort sensation during exercise with induced expiratory-flow limitation in healthy humans.

Détails

ID Serval
serval:BIB_C89690E80E4F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Respiratory effort sensation during exercise with induced expiratory-flow limitation in healthy humans.
Périodique
Journal of Applied Physiology
Auteur(s)
Kayser B., Sliwinski P., Yan S., Tobiasz M., Macklem P.T.
ISSN
8750-7587 (Print)
ISSN-L
0161-7567
Statut éditorial
Publié
Date de publication
1997
Volume
83
Numéro
3
Pages
936-947
Langue
anglais
Résumé
Nine healthy subjects (age 31 +/- 4 yr) exercised with and without expiratory-flow limitation (maximal flow approximately 1 l/s). We monitored flow, end-tidal PCO2, esophageal (Pes) and gastric pressures, changes in end-expiratory lung volume, and perception (sensation) of difficulty in breathing. Subjects cycled at increasing intensity (+25 W/30 s) until symptom limitation. During the flow-limited run, exercise performance was limited in all subjects by maximum sensation. Sensation was equally determined by inspiratory and expiratory pressure changes. In both runs, 90% of the variance in sensation could be explained by the Pes swings (difference between peak inspiratory and peak expiratory Pes). End-tidal PCO2 did not explain any variance in sensation in the control run and added only 3% to the explained variance in the flow-limited run. We conclude that in healthy subjects, during normal as well as expiratory flow-limited exercise, the pleural pressure generation of the expiratory muscles is equally related to the perception of difficulty in breathing as that of the inspiratory muscles.
Mots-clé
Adult, Carbon Dioxide/blood, Diaphragm/physiology, Exercise/physiology, Exercise Test, Female, Humans, Male, Models, Biological, Regression Analysis, Respiratory Function Tests, Respiratory Mechanics/physiology, Respiratory Muscles/physiology
Pubmed
Web of science
Création de la notice
19/09/2013 10:58
Dernière modification de la notice
20/08/2019 16:43
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