Hypothermia is a frequent sign of severe hypoglycaemia in patients with diabetes.

Détails

ID Serval
serval:BIB_C856DF842228
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Hypothermia is a frequent sign of severe hypoglycaemia in patients with diabetes.
Périodique
Diabetes & metabolism
Auteur(s)
Tran C., Gariani K., Herrmann F.R., Juan L., Philippe J., Rutschmann O.T., Vischer U.M.
ISSN
1878-1780 (Electronic)
ISSN-L
1262-3636
Statut éditorial
Publié
Date de publication
10/2012
Peer-reviewed
Oui
Volume
38
Numéro
4
Pages
370-372
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Hypothermia is a recognized complication of severe hypoglycaemia, but its prevalence and characteristics are poorly studied. For this reason, this study aimed to evaluate hypothermia in severely hypoglycaemic patients.
A retrospective chart review was performed including all patients discharged between 2007 and 2010 from the Emergency Department of the Geneva University Hospital with a diagnosis of severe hypoglycaemia.
Hypothermia was identified in 30 (23.4%) out of 128 patients with severe hypoglycaemia. Its incidence was not affected by age, type of diabetes, season or time of day (day/night). Using linear regression, the lowest recorded temperature was associated with the Glasgow coma scale (GCS) score (r2 = 13.8%, P < 0.0001) and inversely associated with the leukocyte count (r2 = 13.1%, P = 0.001).
Hypothermia is a frequent sign of severe hypoglycaemia in patients with diabetes. The associations between hypothermia and the GCS score and the leukocyte count suggest that it is a marker of hypoglycaemia severity and/or duration. Hypothermia may represent an important compensatory mechanism in severe hypoglycaemia, reflecting a decrease in energy demand during glucose deprivation.

Mots-clé
Adult, Emergency Medicine, Female, Glasgow Coma Scale, Humans, Hypoglycemia/blood, Hypoglycemia/chemically induced, Hypoglycemia/complications, Hypoglycemia/diagnosis, Hypoglycemic Agents/administration & dosage, Hypoglycemic Agents/adverse effects, Hypothermia/blood, Hypothermia/etiology, Incidence, Male, Middle Aged, Retrospective Studies
Pubmed
Web of science
Création de la notice
15/10/2017 14:11
Dernière modification de la notice
20/08/2019 16:43
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