Rapid determination of amphetamines by high-performance liquid chromatography with UV detection

Détails

ID Serval
serval:BIB_C75536C6D34E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Rapid determination of amphetamines by high-performance liquid chromatography with UV detection
Périodique
Journal of Chromatography A
Auteur(s)
Sadeghipour  F., Giroud  C., Rivier  L., Veuthey  J. L.
ISSN
0021-9673
Statut éditorial
Publié
Date de publication
1997
Peer-reviewed
Oui
Volume
761
Numéro
1-2
Pages
71-78
Résumé
A liquid chromatographic method with UV detection was developed for the separation and quantification of six amphetamines in the presence of adulterants in illicit drugs. Comparison was made between a regular reversed-phase and a base-deactivated column. The mobile phase composition was optimized by studying the influence of pH, buffer composition and the organic solvent type. Validation was accomplished by examination of the linearity, precision, accuracy, limits of detection and limits of quantification of the method. Amphetamines were quantified in eight tablets obtained from illicit drug seizures and the results were verified by a GC-MS procedure.
Web of science
Création de la notice
08/02/2008 18:44
Dernière modification de la notice
20/08/2019 16:42
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