Interruption de grossesse au cours du premier trimestre. Valeur de la mise en condition pre-operatoire du col uterin de la primigeste par l'application extra-amniotique d'une dose unique de gel de prostaglandine F2-alpha. [First trimester termination of pregnancy. The value of treating the cervix pre-operatively in the primigravid patient by extra-amniotic administration of a single dose of F2-alpha prostaglandin gel (author's transl)]

Détails

ID Serval
serval:BIB_C671F22F96BC
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Interruption de grossesse au cours du premier trimestre. Valeur de la mise en condition pre-operatoire du col uterin de la primigeste par l'application extra-amniotique d'une dose unique de gel de prostaglandine F2-alpha. [First trimester termination of pregnancy. The value of treating the cervix pre-operatively in the primigravid patient by extra-amniotic administration of a single dose of F2-alpha prostaglandin gel (author's transl)]
Périodique
Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
Auteur⸱e⸱s
De Grandi  P., Nguyen  T. H., Kunz  B., Suppan  P.
ISSN
0368-2315 (Print)
Statut éditorial
Publié
Date de publication
1980
Volume
9
Numéro
5
Pages
587-94
Notes
Clinical Trial
Controlled Clinical Trial
English Abstract
Journal Article
Résumé
The authors have tried "priming" the cervix by the administration of a single extraamniotic dose of a F2-alpha prostaglandin gel. This is shown to decrease the risks of trauma associated, with the often difficult, instrumental dilatation of a primigravid cervix at the time of the termination of a 9-12 week pregnancy. The dilatation observed at curettage after this single dose was on the average 10.5 mm +/- 2.2 mm. This is very significantly (p < 0,0001) different from that of patients who received a placebo gel, in which the average diameter of the cervical canal was 4.5 mm +/- 1.0 mm. Constituting a sure and safe method this single priming dose is only applicable when the pain, from the uterine contractions that it produces, can be controlled in an efficient manner. The comparisons made concerning this point, in this paper, show that it can only be done by the use of a continuous epidural anaesthetic. This obviates the necessity of another anaesthetic at the time of aspiration-curettage.
Mots-clé
*Abortion, Induced Cervix Uteri/*drug effects Female Humans Pregnancy Pregnancy Trimester, First Prostaglandins F/*therapeutic use
Pubmed
Web of science
Création de la notice
25/01/2008 15:39
Dernière modification de la notice
20/08/2019 15:41
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