Assessing clinical outcome of transplant patients by means of the INTERMED
Détails
ID Serval
serval:BIB_C61317493233
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Institution
Titre
Assessing clinical outcome of transplant patients by means of the INTERMED
ISBN
0022-3999
Statut éditorial
Publié
Date de publication
2006
Peer-reviewed
Oui
Volume
60
Série
Journal of Psychosomatic Research
Pages
661
Langue
anglais
Notes
SAPHIRID:61569
Résumé
Aim: The objective of this ongoing multicentric study is to evaluate if the INTERMED (IM), a screening instrument to assess case complexity, identifies patients at risk for unfavourable postoperative development.
Methods: So far, 217 kidney (KTX) and liver (LTX) transplant patients were evaluated preoperatively and 70 of them at 12 months post transplant. Biopsychosocial profiles were assessed using the IM. Quality of life [Short Form 36 (SF-36)] and depressive symptomatology (HADS) were measured before transplant (TX) and 1 year after transplantation. Correlations between the IM scores pre transplant and SF-36 and HADS scores at follow-up were studied after controlling for baseline measures.
Results: At baseline, LTX scored higher on the depression subscale, the sum-score of the HADS (P b.001, Mliver/kidney depression 7.81/6.08, Mliver/kidney sum-score 15.1/12.3) and lower on the SF-36 physical-health scale (Mliver/kidney 36.0/42.3). For the whole sample, we could not state a significant relationship between the IM sum-score before TX and SF-36 and HADS measures after TX, but we found a negative correlation between the IM psychological domain and the SF-36 subscale vitality (r=_0.37) and mental health scale (r=_0.50). For KTX, a negative correlation was found between the IM sum-score 1, the biological 2, and the psychological 3 domain and the SF-36 scale physical functioning (r1=_0.56, r2=_0.46, r3=_0.57). For LTX, a negative correlation (r=_0.38) emerged for the IM psychological domain and the SF-36 subscale vitality.
Discussion: This preliminary analysis demonstrates a certain predictive quality of the IM, indicating an association of higher IM scores with an increased risk for poor health-related quality of life after TX. We plan to present an elaborated analysis of our findings at the conference.
Methods: So far, 217 kidney (KTX) and liver (LTX) transplant patients were evaluated preoperatively and 70 of them at 12 months post transplant. Biopsychosocial profiles were assessed using the IM. Quality of life [Short Form 36 (SF-36)] and depressive symptomatology (HADS) were measured before transplant (TX) and 1 year after transplantation. Correlations between the IM scores pre transplant and SF-36 and HADS scores at follow-up were studied after controlling for baseline measures.
Results: At baseline, LTX scored higher on the depression subscale, the sum-score of the HADS (P b.001, Mliver/kidney depression 7.81/6.08, Mliver/kidney sum-score 15.1/12.3) and lower on the SF-36 physical-health scale (Mliver/kidney 36.0/42.3). For the whole sample, we could not state a significant relationship between the IM sum-score before TX and SF-36 and HADS measures after TX, but we found a negative correlation between the IM psychological domain and the SF-36 subscale vitality (r=_0.37) and mental health scale (r=_0.50). For KTX, a negative correlation was found between the IM sum-score 1, the biological 2, and the psychological 3 domain and the SF-36 scale physical functioning (r1=_0.56, r2=_0.46, r3=_0.57). For LTX, a negative correlation (r=_0.38) emerged for the IM psychological domain and the SF-36 subscale vitality.
Discussion: This preliminary analysis demonstrates a certain predictive quality of the IM, indicating an association of higher IM scores with an increased risk for poor health-related quality of life after TX. We plan to present an elaborated analysis of our findings at the conference.
Création de la notice
10/03/2008 11:28
Dernière modification de la notice
20/08/2019 16:41