Post mortem vitreous magnesium in adult population.

Détails

ID Serval
serval:BIB_C528EC82CEA8
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Post mortem vitreous magnesium in adult population.
Périodique
Forensic science international
Auteur(s)
Tse R., Garland J., Kesha K., Morrow P., Lam L., Elstub H., Cala A.D., Palmiere C., Stables S.
ISSN
1872-6283 (Electronic)
ISSN-L
0379-0738
Statut éditorial
Publié
Date de publication
03/2018
Peer-reviewed
Oui
Volume
284
Pages
46-52
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
The study of post mortem vitreous magnesium (Mg) is less common than sodium (Na), chloride (Cl) and potassium (K) in the forensic literature. There is no accepted normal range for post mortem vitreous Mg and the relationship between post mortem vitreous Mg levels and post mortem interval (PMI), other electrolyte levels, disease conditions, age and sex have not been fully established.
To investigate the relationship of post mortem vitreous Mg with age, sex, PMI, vitreous electrolyte levels and diabetic status.
A retrospective study of 20 consecutive cases of diabetics and 20 non-diabetic adult deaths was performed. Spearman correlation and the permutation test were used to explore the relationship between post mortem vitreous Mg and continuous and categorical variables respectively.
The mean post mortem vitreous Mg was 1.03mmol/L (95%CI: 0.98-1.08mmol/L). The absolute Spearman correlation coefficients (rho) between post mortem vitreous Mg with PMI, age, and other vitreous electrolytes (Na, Cl, and K) ranged between 0.04-0.21 (p>0.19). Post mortem vitreous Mg was statistically higher in diabetics (mean difference: 0.08mmol/L; area-under-the-curve=0.65 on receiver-operator-characteristic curve). No statistical difference was demonstrated between sexes (p=0.92).
In our adult population, post mortem vitreous Mg did not correlate with age, PMI, other vitreous electrolytes (sodium, chloride and potassium) or sex. It was higher in diabetics, however had limited utility as a surrogate marker. Overall, post mortem Mg is steady in the early post mortem period with a mean of 1.03mmol/L.
Mots-clé
Adult, Aged, Case-Control Studies, Chlorides/metabolism, Diabetes Mellitus/metabolism, Female, Humans, Magnesium/metabolism, Male, Middle Aged, Postmortem Changes, Potassium/metabolism, Retrospective Studies, Sodium/metabolism, Vitreous Body/metabolism, Young Adult, Chloride, Magnesium, Post mortem, Post mortem interval, Sodium, Vitreous
Pubmed
Web of science
Création de la notice
16/01/2018 9:37
Dernière modification de la notice
20/08/2019 16:40
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