Randomly controlled drivers using minimally invasive sampling: assessment of drug prevalence in Western Switzerland over two time periods.

Détails

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Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_C4890A2DF3E4
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Randomly controlled drivers using minimally invasive sampling: assessment of drug prevalence in Western Switzerland over two time periods.
Périodique
BMC public health
Auteur⸱e⸱s
Joye T., Déglon J., Donzé N., Gilardi F., Sidibé J., Favrat B., Augsburger M., Thomas A.
ISSN
1471-2458 (Electronic)
ISSN-L
1471-2458
Statut éditorial
Publié
Date de publication
28/12/2022
Peer-reviewed
Oui
Volume
22
Numéro
1
Pages
2446
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Résumé
According to the World Health Organization, road traffic injuries lead to 1.3 million deaths each year and represent the leading cause of death for young adults under 30 years old. The use of psychoactive substances, including alcohol, drugs and pharmaceuticals, is a well-known risk factor for road traffic injuries. Our study aims to assess the prevalence of substances consumed by drivers in western Switzerland. Such studies are pivotal to improving prevention and developing public awareness campaigns.
To assess the prevalence of psychoactive substances among drivers, roadside controls were performed in collaboration with local police, using their classical sampling procedures to detect drivers under the influence of drugs or alcohol over two time periods (P1: 2006-2008, P2: 2017-2020). When impaired driving was not suspected by the police, minimally invasive sampling strategies (i.e., oral fluids during P1 and dried blood spots during P2) were performed on volunteer drivers after a road safety survey. A posteriori analyses and statistical interpretation were then performed.
Among the 1605 drivers included in the study, 1048 volunteers provided an oral fluid sample, while 299 provided a dried blood spot sample. The percentage of drivers testing positive for at least one substance that can impact driving abilities was stable over time, with a rate of 10.5% positivity measured over both periods. Considering the different categories of substances, a slight variation was observed between both periods, with 7.6 and 6.3% of pharmaceuticals and 3.6 and 4.9% of illicit drugs for P1 and P2, respectively. Regarding the consumption of illicit drugs, the highest percentage of positivity was measured in biological fluids of drivers under the age of 35, during nights and week-ends, periods which are considered particularly prone to fatal accidents for this age group. Disturbingly, the road safety survey highlighted that drivers' perception of the risk of getting positively controlled while driving after drug consumption is low (3.3 on a 1-to-10 scale, N = 299).
The number of positive cases measured in voluntary drivers who passed the preliminary police check demonstrates the importance of systematic biofluid sampling strategies regarding driving under the influence of psychoactive substances. Although the number of fatal road accidents globally has decreased over time, the results of this study reveal the need for both better prevention and deterrent processes that could potentially reduce the risk of fatal road accidents associated with drug consumption.
Mots-clé
Young Adult, Humans, Infant, Adult, Substance-Related Disorders/epidemiology, Prevalence, Switzerland/epidemiology, Substance Abuse Detection, Illicit Drugs, Ethanol, Accidents, Traffic, Automobile Driving, Dried blood spots, Driving under the influence of drugs, Minimally invasive sampling, Oral fluids, Prevention, Psychoactive substances, Roadside controls
Pubmed
Web of science
Open Access
Oui
Création de la notice
04/01/2023 8:24
Dernière modification de la notice
11/02/2023 6:51
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