About the involvement of deoxyribonuclease I in apoptosis

Détails

ID Serval
serval:BIB_C2B8575789F0
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
About the involvement of deoxyribonuclease I in apoptosis
Périodique
Cell Death and Differentiation
Auteur⸱e⸱s
Peitsch  M. C., Polzar  B., Tschopp  J., Mannherz  H. G.
ISSN
1350-9047 (Print)
Statut éditorial
Publié
Date de publication
07/1994
Volume
1
Numéro
1
Pages
1-6
Notes
Journal Article --- Old month value: Jul
Résumé
Cell death by apoptosis is involved in a large variety of developmental events and physiological processes requiring a reduction in cell count. Nuclear collapse, one of the first visible changes denoting irreversible commitment to cell death by apoptosis, is frequently accompanied by chromatin degradation into nucleosome-sized fragments of multiples thereof. The identity of the endonuclease responsible for this DNA digestion has attracted some interest in recent years and several candidate endonucleases have been proposed. The scope of this article is to summarise the present knowledge about deoxyribonuclease I, one of the candidate enzymes.
Pubmed
Création de la notice
24/01/2008 16:19
Dernière modification de la notice
20/08/2019 16:37
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